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Lamp1 lysosomal-associated membrane protein 1 [ Mus musculus (house mouse) ]

Gene ID: 16783, updated on 8-Dec-2014
Official Symbol
Lamp1provided by MGI
Official Full Name
lysosomal-associated membrane protein 1provided by MGI
Primary source
MGI:MGI:96745
See related
Ensembl:ENSMUSG00000031447
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CD107a; Lamp-1; AI196048
See Lamp1 in Epigenomics, MapViewer
Location:
8 A1.1; 8 5.73 cM
Exon count:
9
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 8 NC_000074.6 (13159135..13175338)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene PCI domain containing 2 Neighboring gene cullin 4A Neighboring gene microRNA 7065 Neighboring gene GH regulated TBC protein 1 Neighboring gene microRNA 1968 Neighboring gene RIKEN cDNA 2810030D12 gene Neighboring gene predicted gene, 34505

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Lysosome, organism-specific biosystem (from KEGG)
    Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
  • Lysosome, conserved biosystem (from KEGG)
    Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
  • Phagosome, organism-specific biosystem (from KEGG)
    Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Phagosome, conserved biosystem (from KEGG)
    Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Tuberculosis, organism-specific biosystem (from KEGG)
    Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Tuberculosis, conserved biosystem (from KEGG)
    Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
Golgi to lysosome transport ISO
Inferred from Sequence Orthology
more info
 
autophagic cell death ISO
Inferred from Sequence Orthology
more info
 
establishment of protein localization to organelle ISO
Inferred from Sequence Orthology
more info
 
granzyme-mediated apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of natural killer cell degranulation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of natural killer cell mediated cytotoxicity ISO
Inferred from Sequence Orthology
more info
 
protein stabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of organelle transport along microtubule ISO
Inferred from Sequence Orthology
more info
 
spermatogenesis TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
alveolar lamellar body ISO
Inferred from Sequence Orthology
more info
 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cytolytic granule IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
endosome IDA
Inferred from Direct Assay
more info
PubMed 
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
late endosome IDA
Inferred from Direct Assay
more info
PubMed 
late endosome ISO
Inferred from Sequence Orthology
more info
 
lysosome IDA
Inferred from Direct Assay
more info
PubMed 
lysosome ISO
Inferred from Sequence Orthology
more info
 
melanosome IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
multivesicular body IDA
Inferred from Direct Assay
more info
PubMed 
multivesicular body ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
phagolysosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 
synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
vacuole ISO
Inferred from Sequence Orthology
more info
 
vesicle IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
lysosome-associated membrane glycoprotein 1
Names
lysosome-associated membrane glycoprotein 1
P2B
LGP-A
Lamp I
LGP-120
lysosomal membrane glycoprotein 1
lysosomal membrane glycoprotein A
CD107 antigen-like family member A
lysosome-associated membrane protein 1
120 kDa lysosomal membrane glycoprotein
LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010684.2NP_034814.2  lysosome-associated membrane glycoprotein 1 precursor

    See proteins identical to NP_034814.2

    Status: VALIDATED

    Source sequence(s)
    AA154440, AI120997, AK159376, BC049097
    Consensus CDS
    CCDS22106.1
    UniProtKB/Swiss-Prot
    P11438
    UniProtKB/TrEMBL
    Q3TA96
    UniProtKB/TrEMBL
    Q3TX84
    Related
    ENSMUSP00000033824, ENSMUST00000033824
    Conserved Domains (2) summary
    cd12087
    Location:371400
    TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
    pfam01299
    Location:105406
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000074.6 

    Range
    13159135..13175338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000030.1 

    Range
    13327454..13343657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)