Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    SOD1 superoxide dismutase SOD1 [ Saccharomyces cerevisiae S288c ]

    Gene ID: 853568, updated on 7-Aug-2016
    Gene symbol
    SOD1
    Gene description
    superoxide dismutase SOD1
    Primary source
    SGD:S000003865
    Locus tag
    YJR104C
    Gene type
    protein coding
    RNA name
    superoxide dismutase SOD1
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CRS4
    See SOD1 in Map Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (622550..623014, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene ESCRT-II subunit protein VPS25 Neighboring gene CTP synthase URA8 Neighboring gene adenosine kinase Neighboring gene Ecm27p

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    antioxidant activity IEA
    Inferred from Electronic Annotation
    more info
     
    copper ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    superoxide dismutase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    superoxide dismutase activity IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial intermembrane space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    superoxide dismutase SOD1
    NP_012638.1
    • Cytosolic copper-zinc superoxide dismutase; detoxifies superoxide; stabilizes Yck1p and Yck2p kinases in glucose to repress respiration; phosphorylated by Dun1p, enters nucleus under oxidative stress to promote transcription of stress response genes; human ortholog SOD1 implicated in ALS and complements yeast null; abundance increases under DNA replication stress and during exposure to boric acid; localization to mitochondrial intermembrane space is modulated by MICOS complex

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      622550..623014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181762.1NP_012638.1  superoxide dismutase SOD1 [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_012638.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P00445
      Conserved Domains (1) summary
      cd00305
      Location:2147
      Cu-Zn_Superoxide_Dismutase; Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the ...