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    Egfl7 EGF-like domain 7 [ Mus musculus (house mouse) ]

    Gene ID: 353156, updated on 17-Sep-2016
    Official Symbol
    Egfl7provided by MGI
    Official Full Name
    EGF-like domain 7provided by MGI
    Primary source
    MGI:MGI:2449923
    See related
    Ensembl:ENSMUSG00000026921 Vega:OTTMUSG00000011579
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zneu1; VE-statin
    Orthologs
    Location:
    2; 2 B
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (26581056..26592682)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (26436576..26448202)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35978 Neighboring gene predicted gene, 36171 Neighboring gene microRNA 126a Neighboring gene microRNA 126b Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) Neighboring gene predicted gene, 39772

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Notch binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    calcium ion binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    blood vessel development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of Notch signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell migration IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of endothelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell migration TAS
    Traceable Author Statement
    more info
    PubMed 
    vasculogenesis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular matrix ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    epidermal growth factor-like protein 7
    Names
    EGF-like protein 7
    NEU1 protein
    NOTCH4-like protein
    multiple EGF-like domains protein 7
    multiple epidermal growth factor-like domains protein 7
    vascular endothelial statin

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164564.1NP_001158036.1  epidermal growth factor-like protein 7 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001158036.1

      Status: VALIDATED

      Source sequence(s)
      AK139377, BB871615, CF949270
      Consensus CDS
      CCDS15807.2
      UniProtKB/Swiss-Prot
      Q9QXT5
      UniProtKB/TrEMBL
      Q3UTJ7
      Related
      ENSMUSP00000134034, OTTMUSP00000012332, ENSMUST00000174211, OTTMUST00000027059
      Conserved Domains (3) summary
      cd00054
      Location:114139
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07546
      Location:4597
      EMI; EMI domain
      pfam07645
      Location:141180
      EGF_CA; Calcium-binding EGF domain
    2. NM_178444.4NP_848538.3  epidermal growth factor-like protein 7 isoform 1 precursor

      See identical proteins and their annotated locations for NP_848538.3

      Status: VALIDATED

      Source sequence(s)
      AL732311, BX649422
      Consensus CDS
      CCDS15807.2
      UniProtKB/Swiss-Prot
      Q9QXT5
      UniProtKB/TrEMBL
      Q3UTJ7
      Related
      ENSMUSP00000128741, OTTMUSP00000012328, ENSMUST00000166920, OTTMUST00000027055
      Conserved Domains (3) summary
      cd00054
      Location:114139
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07546
      Location:4597
      EMI; EMI domain
      pfam07645
      Location:141180
      EGF_CA; Calcium-binding EGF domain
    3. NM_198724.2NP_942017.2  epidermal growth factor-like protein 7 isoform 1 precursor

      See identical proteins and their annotated locations for NP_942017.2

      Status: VALIDATED

      Source sequence(s)
      AL732311, BX649422
      Consensus CDS
      CCDS15807.2
      UniProtKB/Swiss-Prot
      Q9QXT5
      UniProtKB/TrEMBL
      Q3UTJ7
      Related
      ENSMUSP00000099971, OTTMUSP00000012330, ENSMUST00000102907, OTTMUST00000027057
      Conserved Domains (3) summary
      cd00054
      Location:114139
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07546
      Location:4597
      EMI; EMI domain
      pfam07645
      Location:141180
      EGF_CA; Calcium-binding EGF domain
    4. NM_198725.2NP_942018.2  epidermal growth factor-like protein 7 isoform 2 precursor

      See identical proteins and their annotated locations for NP_942018.2

      Status: VALIDATED

      Source sequence(s)
      AK002601, AW491662, BY274501
      Consensus CDS
      CCDS15808.2
      UniProtKB/Swiss-Prot
      Q9QXT5
      UniProtKB/TrEMBL
      A0A0R4J189
      Related
      ENSMUSP00000097863, OTTMUSP00000012329, ENSMUST00000100290, OTTMUST00000027056
      Conserved Domains (3) summary
      cd00054
      Location:114139
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07546
      Location:4597
      EMI; EMI domain
      pfam07645
      Location:141180
      EGF_CA; Calcium-binding EGF domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      26581056..26592682
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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