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    KDM6A lysine (K)-specific demethylase 6A [ Homo sapiens (human) ]

    Gene ID: 7403, updated on 26-Jul-2015
    Official Symbol
    KDM6Aprovided by HGNC
    Official Full Name
    lysine (K)-specific demethylase 6Aprovided by HGNC
    Primary source
    HGNC:HGNC:12637
    See related
    Ensembl:ENSG00000147050; HPRD:02131; MIM:300128; Vega:OTTHUMG00000021402
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    UTX; KABUK2; bA386N14.2
    Summary
    This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
    Orthologs
    See KDM6A in Epigenomics, MapViewer
    Location:
    Xp11.2
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) X NC_000023.11 (44873175..45112779)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (44732419..44972024)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373190 Neighboring gene dual specificity phosphatase 21 Neighboring gene chromosome X open reading frame 36 Neighboring gene uncharacterized LOC105373191

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Associated conditions

    Description Tests
    Kabuki make-up syndrome
    MedGen: C0796004 OMIM: 147920 GeneReviews: Kabuki Syndrome
    Compare labs
    Kabuki syndrome 2
    MedGen: C3275495 OMIM: 300867 GeneReviews: Not available
    Compare labs

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated (2013-07-18)

    ClinGen Genome Curation Page
    Haploinsufficency

    Sufficient evidence for dosage pathogenicity (Last evaluated (2013-07-18)

    ClinGen Genome Curation PagePubMed
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC141941, DKFZp686A03225

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    RNA polymerase II core promoter proximal region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    histone demethylase activity (H3-K27 specific) IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin organization TAS
    Traceable Author Statement
    more info
     
    heart morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    histone H3-K27 demethylation IEA
    Inferred from Electronic Annotation
    more info
     
    histone H3-K4 methylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    in utero embryonic development IEA
    Inferred from Electronic Annotation
    more info
     
    mesodermal cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism growth IEA
    Inferred from Electronic Annotation
    more info
     
    neural tube closure IEA
    Inferred from Electronic Annotation
    more info
     
    notochord morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
     
    respiratory system process IEA
    Inferred from Electronic Annotation
    more info
     
    somite rostral/caudal axis specification IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    histone methyltransferase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleoplasm TAS
    Traceable Author Statement
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    lysine-specific demethylase 6A
    Names
    bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX))
    histone demethylase UTX
    ubiquitously transcribed tetratricopeptide repeat protein X-linked
    ubiquitously-transcribed TPR gene on the X chromosome

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016260.1 RefSeqGene

      Range
      4999..244435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_616

    mRNA and Protein(s)

    1. NM_001291415.1NP_001278344.1  lysine-specific demethylase 6A isoform 1

      See identical proteins and their annotated locations for NP_001278344.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AI364446, AL041377, AL831996, BC143277, BC143278, DC381812
      UniProtKB/TrEMBL
      B7ZKN5
      UniProtKB/TrEMBL
      B7ZKN6
      UniProtKB/TrEMBL
      Q86TD1
      Related
      ENSP00000483595, ENST00000611820
      Conserved Domains (6) summary
      pfam02373
      Location:11851293
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11511215
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106399
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    2. NM_001291416.1NP_001278345.1  lysine-specific demethylase 6A isoform 2

      See identical proteins and their annotated locations for NP_001278345.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AI364446, AL041377, AL831996, BC143272, BC143278, DC381812
      UniProtKB/TrEMBL
      B7ZKN1
      UniProtKB/TrEMBL
      B7ZKN6
      UniProtKB/TrEMBL
      Q86TD1
      Related
      ENSP00000372355, ENST00000382899
      Conserved Domains (6) summary
      pfam02373
      Location:11401248
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11061170
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106401
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    3. NM_001291417.1NP_001278346.1  lysine-specific demethylase 6A isoform 4

      See identical proteins and their annotated locations for NP_001278346.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks two consecutive in-frame exons in the coding region, compared to variant 1. The resulting isoform (4) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AI364446, AK303430, AL041377, AL831996, BC143278, DC381812
      UniProtKB/TrEMBL
      B4E0L8
      UniProtKB/TrEMBL
      B7ZKN6
      UniProtKB/TrEMBL
      Q86TD1
      Related
      ENSP00000437405, ENST00000536777
      Conserved Domains (7) summary
      pfam02373
      Location:10881196
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10541118
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:128194
      TPR_11; TPR repeat
      pfam13424
      Location:205282
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    4. NM_001291418.1NP_001278347.1  lysine-specific demethylase 6A isoform 5

      See identical proteins and their annotated locations for NP_001278347.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks two consecutive in-frame exons and a single in-frame exon in the coding region, compared to variant 1. The resulting isoform (5) lacks two internal segments, compared to isoform 1.
      Source sequence(s)
      AB208795, AI364446, AL041377, BC143278, DC381812, DQ062677
      UniProtKB/TrEMBL
      B7ZKN6
      UniProtKB/TrEMBL
      E1U0S6
      UniProtKB/TrEMBL
      Q59HG3
      Conserved Domains (7) summary
      pfam02373
      Location:10541162
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10201084
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:128194
      TPR_11; TPR repeat
      pfam13424
      Location:205282
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    5. NM_001291421.1NP_001278350.1  lysine-specific demethylase 6A isoform 6

      See identical proteins and their annotated locations for NP_001278350.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks an internal exon in the 5' region, which results in translation initiation from a downstream start codon, and also lacks two consecutive in-frame exons in the coding region, compared to variant 1. The resulting isoform (6) has a shorter N-terminus and lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AI364446, AL041377, AL831996, BC143275, BC143278, DC381812
      UniProtKB/TrEMBL
      B7ZKN6
      UniProtKB/TrEMBL
      Q86TD1
      Conserved Domains (6) summary
      pfam02373
      Location:837945
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:803867
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      pfam00515
      Location:67100
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:3197
      TPR_11; TPR repeat
      pfam13431
      Location:2152
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:34113
      TPR; putative protein binding surface [polypeptide binding]
    6. NM_021140.3NP_066963.2  lysine-specific demethylase 6A isoform 3

      See identical proteins and their annotated locations for NP_066963.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AB208795, AI364446, AL041377, DC381812
      Consensus CDS
      CCDS14265.1
      UniProtKB/Swiss-Prot
      O15550
      UniProtKB/TrEMBL
      Q59HG3
      Related
      ENSP00000367203, OTTHUMP00000023175, ENST00000377967, OTTHUMT00000056324
      Conserved Domains (6) summary
      pfam02373
      Location:11331241
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10991163
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106399
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]

    RNA

    1. NR_111960.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) lacks two internal exons and has an alternate splice site in an internal exon,, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translation start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AB208795, AI364446, AK303430, AL041377, BC143272, DC381812, EU026291

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p2 Primary Assembly

      Range
      44873175..45112779
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011543957.1XP_011542259.1  

      Conserved Domains (6) summary
      pfam02373
      Location:12041312
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11701234
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145418
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    2. XM_011543960.1XP_011542262.1  

      Conserved Domains (6) summary
      pfam02373
      Location:12041312
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11701234
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145418
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    3. XM_011543959.1XP_011542261.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11701278
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11361200
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145418
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    4. XM_011543962.1XP_011542264.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11521260
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11181182
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145418
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    5. XM_011543967.1XP_011542269.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11521260
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11181182
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145418
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    6. XM_011543966.1XP_011542268.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11181226
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10841148
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145418
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    7. XM_011543961.1XP_011542263.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11591267
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11251189
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145420
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    8. XM_011543965.1XP_011542267.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11251233
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10911155
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145420
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    9. XM_011543971.1XP_011542273.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11251233
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10911155
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145420
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    10. XM_011543968.1XP_011542270.1  

      Conserved Domains (7) summary
      pfam02373
      Location:11071215
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10731137
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:148213
      TPR_11; TPR repeat
      pfam13424
      Location:224301
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    11. XM_011543973.1XP_011542275.1  

      Conserved Domains (7) summary
      pfam02373
      Location:11071215
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10731137
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:148213
      TPR_11; TPR repeat
      pfam13424
      Location:224301
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    12. XM_011543958.1XP_011542260.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11851293
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11511215
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106399
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    13. XM_005272656.3XP_005272713.1  

      See identical proteins and their annotated locations for XP_005272713.1

      Conserved Domains (6) summary
      pfam02373
      Location:11511259
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11171181
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106399
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    14. XM_011543964.1XP_011542266.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11331241
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10991163
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106399
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    15. XM_011543970.1XP_011542272.1  

      Conserved Domains (6) summary
      pfam02373
      Location:10991207
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10651129
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106399
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    16. XM_005272659.3XP_005272716.1  

      See identical proteins and their annotated locations for XP_005272716.1

      Conserved Domains (6) summary
      pfam02373
      Location:10991207
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10651129
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106399
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    17. XM_011543963.1XP_011542265.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11401248
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11061170
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106401
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    18. XM_011543969.1XP_011542271.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11061214
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10721136
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106401
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    19. XM_011543972.1XP_011542274.1  

      Conserved Domains (7) summary
      pfam02373
      Location:10881196
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10541118
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:128194
      TPR_11; TPR repeat
      pfam13424
      Location:205282
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    20. XM_011543974.1XP_011542276.1  

      Conserved Domains (6) summary
      pfam02373
      Location:11331241
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10991163
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:106399
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:130163
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:272303
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:285364
      TPR; putative protein binding surface [polypeptide binding]
    21. XM_011543976.1XP_011542278.1  

      Conserved Domains (5) summary
      smart00558
      Location:11701215
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:145418
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam00515
      Location:149182
      TPR_1; Tetratricopeptide repeat
      pfam13431
      Location:291322
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:304383
      TPR; putative protein binding surface [polypeptide binding]
    22. XM_011543975.1XP_011542277.1  

      Related
      ENSP00000398929, OTTHUMP00000023177, ENST00000433797, OTTHUMT00000056326
      Conserved Domains (6) summary
      pfam02373
      Location:9341042
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:900964
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      pfam00515
      Location:67100
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:3197
      TPR_11; TPR repeat
      pfam13431
      Location:2152
      TPR_17; Tetratricopeptide repeat
      sd00006
      Location:34113
      TPR; putative protein binding surface [polypeptide binding]

    RNA

    1. XR_949018.1 RNA Sequence

    Alternate CHM1_1.1

    Genomic

    1. NC_018934.2 Alternate CHM1_1.1

      Range
      44765275..45004750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)