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Fermt3 fermitin family homolog 3 (Drosophila) [ Mus musculus (house mouse) ]

Gene ID: 108101, updated on 21-Jul-2014
Official Symbol
Fermt3provided by MGI
Official Full Name
fermitin family homolog 3 (Drosophila)provided by MGI
Primary source
MGI:2147790
See related
Ensembl:ENSMUSG00000024965
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C79673; Kindlin3
See Fermt3 in Epigenomics, MapViewer
Location:
19 A; 19
Exon count :
15
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 19 NC_000085.6 (6998958..7019480, complement)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102639551 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 4 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 22 Neighboring gene tRNA phosphotransferase 1 Neighboring gene stress-induced phosphoprotein 1 Neighboring gene uncharacterized LOC102639820 Neighboring gene MACRO domain containing 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Platelet activation, organism-specific biosystem (from KEGG)
    Platelet activation, organism-specific biosystemPlatelets play a key and beneficial role for primary hemostasis on the disruption of the integrity of vessel wall. Platelet adhesion and activation at sites of vascular wall injury is initiated by ad...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
integrin binding IDA
Inferred from Direct Assay
more info
PubMed 
integrin binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
integrin activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
integrin activation ISO
Inferred from Sequence Orthology
more info
 
leukocyte cell-cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
leukocyte cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
platelet aggregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell-cell adhesion mediated by integrin IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell-cell adhesion mediated by integrin ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
podosome IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
fermitin family homolog 3
Names
fermitin family homolog 3
unc-112-related protein 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153795.2NP_722490.1  fermitin family homolog 3

    See proteins identical to NP_722490.1

    Status: VALIDATED

    Source sequence(s)
    AC163098, AK142912
    Consensus CDS
    CCDS29518.1
    UniProtKB/TrEMBL
    Q3TEE6
    UniProtKB/Swiss-Prot
    Q8K1B8
    Related
    ENSMUSP00000037858, ENSMUST00000040772
    Conserved Domains (4) summary
    smart00295
    Location:221301
    Blast Score: 195
    B41; Band 4.1 homologues
    cd01237
    Location:350459
    Blast Score: 563
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:552641
    Blast Score: 436
    FERM_C_fermitin; Fermitin family FERM domain C-lobe
    pfam00373
    Location:507555
    Blast Score: 162
    FERM_M; FERM central domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000085.6 

    Range
    6998958..7019480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526596.1XP_006526659.1  

    Conserved Domains (4) summary
    smart00295
    Location:221301
    Blast Score: 196
    B41; Band 4.1 homologues
    cd01237
    Location:350468
    Blast Score: 543
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:561650
    Blast Score: 436
    FERM_C_fermitin; Fermitin family FERM domain C-lobe
    pfam00373
    Location:516564
    Blast Score: 162
    FERM_M; FERM central domain
  2. XM_006526595.1XP_006526658.1  

    See proteins identical to XP_006526658.1

    Conserved Domains (4) summary
    smart00295
    Location:143223
    Blast Score: 197
    B41; Band 4.1 homologues
    cd01237
    Location:272381
    Blast Score: 563
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:474563
    Blast Score: 437
    FERM_C_fermitin; Fermitin family FERM domain C-lobe
    pfam00373
    Location:429477
    Blast Score: 162
    FERM_M; FERM central domain
  3. XM_006526594.1XP_006526657.1  

    See proteins identical to XP_006526657.1

    Conserved Domains (4) summary
    smart00295
    Location:143223
    Blast Score: 197
    B41; Band 4.1 homologues
    cd01237
    Location:272381
    Blast Score: 563
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:474563
    Blast Score: 437
    FERM_C_fermitin; Fermitin family FERM domain C-lobe
    pfam00373
    Location:429477
    Blast Score: 162
    FERM_M; FERM central domain
  4. XM_006526593.1XP_006526656.1  

    See proteins identical to XP_006526656.1

    UniProtKB/TrEMBL
    Q3TEE6
    UniProtKB/Swiss-Prot
    Q8K1B8
    Conserved Domains (4) summary
    smart00295
    Location:221301
    Blast Score: 195
    B41; Band 4.1 homologues
    cd01237
    Location:350459
    Blast Score: 563
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:552641
    Blast Score: 436
    FERM_C_fermitin; Fermitin family FERM domain C-lobe
    pfam00373
    Location:507555
    Blast Score: 162
    FERM_M; FERM central domain

Alternate Mm_Celera

Genomic

  1. AC_000041.1 

    Range
    6776072..6796571
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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