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    RAD23 Rad23p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856674, updated on 3-Jul-2016
    Gene symbol
    RAD23
    Gene description
    Rad23p
    Primary source
    SGD:S000000763
    Locus tag
    YEL037C
    Gene type
    protein coding
    RNA name
    Rad23p
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    See RAD23 in Map Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (81407..82603, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene cytochrome c isoform 2 Neighboring gene putative acireductone synthase UTR4 Neighboring gene Anp1p Neighboring gene Utr5p

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    damaged DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    proteasome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding, bridging IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ubiquitin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    ER-associated ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
     
    proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    proteasome-mediated ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein deglycosylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleotide-excision repair factor 2 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    proteasome complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    proteasome complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Names
    Rad23p
    NP_010877.3
    • Protein with ubiquitin-like N terminus; subunit of Nuclear Excision Repair Factor 2 (NEF2) with Rad4p that binds damaged DNA; enhances protein deglycosylation activity of Png1p; also involved, with Rad4p, in ubiquitylated protein turnover; Rad4p-Rad23p heterodimer binds to promoters of DNA damage response genes to repress their transcription in the absence of DNA damage

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      81407..82603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178852.3NP_010877.3  Rad23p [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_010877.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P32628
      Conserved Domains (6) summary
      cd01805
      Location:276
      RAD23_N; Ubiquitin-like domain of RAD23
      pfam09280
      Location:260311
      XPC-binding; XPC-binding domain
      COG5272
      Location:317374
      UBI4; Ubiquitin [Posttranslational modification, protein turnover, chaperones]
      cd14378
      Location:142188
      UBA1_Rhp23p_like; UBA1 domain of Schizosaccharomyces pombe UV excision repair protein Rhp23p and its homologs
      cd14381
      Location:356395
      UBA2_Rhp23p_like; UBA2 domain of Schizosaccharomyces pombe UV excision repair protein Rhp23p and its fungal homologs
      TIGR00601
      Location:2398
      rad23; UV excision repair protein Rad23