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Nras neuroblastoma ras oncogene [ Mus musculus (house mouse) ]

Gene ID: 18176, updated on 24-Jan-2015
Official Symbol
Nrasprovided by MGI
Official Full Name
neuroblastoma ras oncogeneprovided by MGI
Primary source
MGI:MGI:97376
See related
Ensembl:ENSMUSG00000027852; Vega:OTTMUSG00000021269
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
N-ras; AV095280
See Nras in MapViewer
Location:
3 F2.2; 3 45.25 cM
Exon count:
10
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 3 NC_000069.6 (103058285..103067914)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene suppressor of IKBKE 1 Neighboring gene cold shock domain containing E1, RNA binding Neighboring gene adenosine monophosphate deaminase 1 Neighboring gene DENN/MADD domain containing 2C

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity TAS
Traceable Author Statement
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein complex binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
GTP catabolic process TAS
Traceable Author Statement
more info
PubMed 
Ras protein signal transduction TAS
Traceable Author Statement
more info
PubMed 
negative regulation of skeletal muscle tissue development IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of skeletal muscle tissue development IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of cell cycle TAS
Traceable Author Statement
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
intracellular TAS
Traceable Author Statement
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
GTPase NRas
Names
GTPase NRas
transforming protein N-Ras

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010937.2NP_035067.2  GTPase NRas precursor

    See proteins identical to NP_035067.2

    Status: VALIDATED

    Source sequence(s)
    AC163297, AK165960, BY321840, CT010359
    Consensus CDS
    CCDS38570.1
    UniProtKB/TrEMBL
    Q3TMF4
    UniProtKB/TrEMBL
    Q4FJP3
    UniProtKB/TrEMBL
    Q9D091
    Related
    ENSMUSP00000029445, OTTMUSP00000023521, ENSMUST00000029445, OTTMUST00000050411
    Conserved Domains (2) summary
    cd04138
    Location:3164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    COG1100
    Location:16165
    COG1100; GTPase SAR1 and related small G proteins [General function prediction only]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000069.6 

    Range
    103058285..103067914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501123.1XP_006501186.1  

    See proteins identical to XP_006501186.1

    UniProtKB/TrEMBL
    Q9D091
    Conserved Domains (2) summary
    cd04138
    Location:3164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    COG1100
    Location:16165
    COG1100; GTPase SAR1 and related small G proteins [General function prediction only]
  2. XM_006501121.1XP_006501184.1  

    See proteins identical to XP_006501184.1

    UniProtKB/TrEMBL
    Q9D091
    Conserved Domains (2) summary
    cd04138
    Location:3164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    COG1100
    Location:16165
    COG1100; GTPase SAR1 and related small G proteins [General function prediction only]
  3. XM_006501120.1XP_006501183.1  

    See proteins identical to XP_006501183.1

    UniProtKB/TrEMBL
    Q9D091
    Conserved Domains (2) summary
    cd04138
    Location:3164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    COG1100
    Location:16165
    COG1100; GTPase SAR1 and related small G proteins [General function prediction only]
  4. XM_006501118.1XP_006501181.1  

    See proteins identical to XP_006501181.1

    Conserved Domains (2) summary
    cd04138
    Location:34195
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    pfam00071
    Location:47196
    Ras; Ras family
  5. XM_006501119.1XP_006501182.1  

    See proteins identical to XP_006501182.1

    Conserved Domains (2) summary
    cd04138
    Location:34195
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    pfam00071
    Location:47196
    Ras; Ras family
  6. XM_006501122.1XP_006501185.1  

    See proteins identical to XP_006501185.1

    UniProtKB/TrEMBL
    Q9D091
    Conserved Domains (2) summary
    cd04138
    Location:3164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
    COG1100
    Location:16165
    COG1100; GTPase SAR1 and related small G proteins [General function prediction only]

Alternate Mm_Celera

Genomic

  1. AC_000025.1 

    Range
    105263160..105272744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)