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    HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor [ Homo sapiens (human) ]

    Gene ID: 55662, updated on 9-Aug-2015
    Official Symbol
    HIF1ANprovided by HGNC
    Official Full Name
    hypoxia inducible factor 1, alpha subunit inhibitorprovided by HGNC
    Primary source
    HGNC:HGNC:17113
    See related
    HPRD:09426; MIM:606615
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FIH1
    Orthologs
    See HIF1AN in Epigenomics, MapViewer
    Location:
    10q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) 10 NC_000010.11 (100535884..100553924)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (102295641..102313681)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene SEC31 homolog B, COPII coat complex component Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa Neighboring gene uncharacterized LOC102724225 Neighboring gene paired box 2

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NHGRI GWAS Catalog

    Description
    Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu
    NHGRI GWA Catalog
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • FLJ20615, FLJ22027, DKFZp762F1811

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol TAS
    Traceable Author Statement
    more info
     
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    colocalizes_with nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    hypoxia-inducible factor 1-alpha inhibitor
    Names
    FIH-1
    factor inhibiting HIF-1
    factor inhibiting HIF1
    hypoxia-inducible factor asparagine hydroxylase
    peptide-aspartate beta-dioxygenase
    NP_060372.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017902.2NP_060372.2  hypoxia-inducible factor 1-alpha inhibitor

      See identical proteins and their annotated locations for NP_060372.2

      Status: VALIDATED

      Source sequence(s)
      AF395830, AL133352, AW015561
      Consensus CDS
      CCDS7498.1
      UniProtKB/Swiss-Prot
      Q9NWT6
      Conserved Domains (1) summary
      pfam13621
      Location:53297
      Cupin_8; Cupin-like domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p2 Primary Assembly

      Range
      100535884..100553924
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011539941.1XP_011538243.1  

      Conserved Domains (1) summary
      pfam13621
      Location:3190
      Cupin_8; Cupin-like domain
    2. XM_011539940.1XP_011538242.1  

      Conserved Domains (1) summary
      pfam13621
      Location:80317
      Cupin_8; Cupin-like domain

    Alternate CHM1_1.1

    Genomic

    1. NC_018921.2 Alternate CHM1_1.1

      Range
      102580289..102598327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)