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Il17a interleukin 17A [ Mus musculus (house mouse) ]

Gene ID: 16171, updated on 24-Jan-2015
Official Symbol
Il17aprovided by MGI
Official Full Name
interleukin 17Aprovided by MGI
Primary source
MGI:MGI:107364
See related
Ensembl:ENSMUSG00000025929; Vega:OTTMUSG00000033825
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Il17; Ctla8; IL-17; Ctla-8; IL-17A
Orthologs
See Il17a in MapViewer
Location:
1; 1 A
Exon count:
3
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 1 NC_000067.6 (20730905..20734496)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene microRNA 206 Neighboring gene microRNA 133b Neighboring gene interleukin 17F Neighboring gene minichromosome maintenance deficient 3 (S. cerevisiae)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Inflammatory bowel disease (IBD), organism-specific biosystem (from KEGG)
    Inflammatory bowel disease (IBD), organism-specific biosystemInflammatory bowel disease (IBD), which includes Crohn disease (CD) and ulcerative colitis (UC), is characterized by chronic inflammation of the gastrointestinal tract due to environmental and geneti...
  • Inflammatory bowel disease (IBD), conserved biosystem (from KEGG)
    Inflammatory bowel disease (IBD), conserved biosystemInflammatory bowel disease (IBD), which includes Crohn disease (CD) and ulcerative colitis (UC), is characterized by chronic inflammation of the gastrointestinal tract due to environmental and geneti...
  • Rheumatoid arthritis, organism-specific biosystem (from KEGG)
    Rheumatoid arthritis, organism-specific biosystemRheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune...
  • Rheumatoid arthritis, conserved biosystem (from KEGG)
    Rheumatoid arthritis, conserved biosystemRheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cytokine activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
interleukin-17A
Names
interleukin-17A
cytotoxic T-lymphocyte-associated antigen 8

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010552.3NP_034682.1  interleukin-17A precursor

    See proteins identical to NP_034682.1

    Status: PROVISIONAL

    Source sequence(s)
    AK040420
    Consensus CDS
    CCDS14842.1
    UniProtKB/TrEMBL
    Q544E6
    UniProtKB/Swiss-Prot
    Q62386
    Related
    ENSMUSP00000027061, OTTMUSP00000046003, ENSMUST00000027061, OTTMUST00000085210
    Conserved Domains (1) summary
    pfam06083
    Location:71150
    IL17; Interleukin-17

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000067.6 

    Range
    20730905..20734496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 

    Range
    20604456..20608046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)