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Arsa arylsulfatase A [ Mus musculus (house mouse) ]

Gene ID: 11883, updated on 12-May-2015
Official Symbol
Arsaprovided by MGI
Official Full Name
arylsulfatase Aprovided by MGI
Primary source
MGI:MGI:88077
See related
Ensembl:ENSMUSG00000022620; Vega:OTTMUSG00000035225
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ASA; As2; AS-A; As-2; TISP73; AW212749
Orthologs
See Arsa in MapViewer
Location:
15; 15 E
Exon count:
8
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (89472476..89477424, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (89302907..89307855, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105246016 Neighboring gene mitogen-activated protein kinase 8 interacting protein 2 Neighboring gene RIKEN cDNA C230037L18 gene Neighboring gene predicted gene, 41381 Neighboring gene uncharacterized LOC105246018 Neighboring gene SH3/ankyrin domain gene 3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
arylsulfatase activity ISO
Inferred from Sequence Orthology
more info
 
calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
cerebroside-sulfatase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
sulfuric ester hydrolase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
autophagy ISO
Inferred from Sequence Orthology
more info
 
binding of sperm to zona pellucida IMP
Inferred from Mutant Phenotype
more info
PubMed 
central nervous system development ISO
Inferred from Sequence Orthology
more info
 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
response to estrogen ISO
Inferred from Sequence Orthology
more info
 
response to ethanol ISO
Inferred from Sequence Orthology
more info
 
response to methylmercury ISO
Inferred from Sequence Orthology
more info
 
response to nutrient ISO
Inferred from Sequence Orthology
more info
 
response to pH ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
acrosomal vesicle ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
endosome ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
extrinsic component of external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
lysosome ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
arylsulfatase A
Names
arylsulfatase A
cerebroside-sulfatase
NP_033843.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009713.4NP_033843.2  arylsulfatase A precursor

    See identical proteins and their annotated locations for NP_033843.2

    Status: VALIDATED

    Source sequence(s)
    AC137513
    Consensus CDS
    CCDS27753.1
    UniProtKB/Swiss-Prot
    P50428
    Related
    ENSMUSP00000127646, OTTMUSP00000049092, ENSMUST00000165199, OTTMUST00000089775
    Conserved Domains (3) summary
    COG3119
    Location:16440
    AslA; Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]
    pfam00884
    Location:20345
    Sulfatase; Sulfatase
    pfam14707
    Location:367501
    Sulfatase_C; C-terminal region of aryl-sulfatase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    89472476..89477424
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245446.1XP_011243748.1  

    See identical proteins and their annotated locations for XP_011243748.1

    Conserved Domains (3) summary
    COG3119
    Location:16440
    AslA; Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]
    pfam00884
    Location:20345
    Sulfatase; Sulfatase
    pfam14707
    Location:367501
    Sulfatase_C; C-terminal region of aryl-sulfatase

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    91601657..91606605
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)