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Cck cholecystokinin [ Rattus norvegicus (Norway rat) ]

Gene ID: 25298, updated on 10-Sep-2014
Official Symbol
Cckprovided by RGD
Official Full Name
cholecystokininprovided by RGD
Primary source
RGD:2288
See related
Ensembl:ENSRNOG00000019321
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
brain-gut peptide with hemacrine and autocrine function in the gut [RGD, Feb 2006]
See Cck in MapViewer
Location:
8q32
Exon count:
4
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (130120524..130127295, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (129312785..129319582, complement)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene unc-51 like kinase 4 Neighboring gene trafficking protein, kinesin binding 1 Neighboring gene ATPase inhibitory factor 1 Neighboring gene uncharacterized LOC102550775 Neighboring gene lysozyme-like 4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
hormone activity IDA
Inferred from Direct Assay
more info
PubMed 
hormone activity NAS
Non-traceable Author Statement
more info
PubMed 
neuropeptide hormone activity IDA
Inferred from Direct Assay
more info
PubMed 
neuropeptide hormone activity ISO
Inferred from Sequence Orthology
more info
 
neuropeptide hormone activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
axonogenesis ISO
Inferred from Sequence Orthology
more info
 
axonogenesis ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
behavioral fear response IMP
Inferred from Mutant Phenotype
more info
PubMed 
eating behavior IDA
Inferred from Direct Assay
more info
PubMed 
eating behavior ISO
Inferred from Sequence Orthology
more info
 
eating behavior ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
negative regulation of appetite IDA
Inferred from Direct Assay
more info
PubMed 
neuron migration ISO
Inferred from Sequence Orthology
more info
 
neuron migration ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of mitochondrial depolarization IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of protein oligomerization IDA
Inferred from Direct Assay
more info
PubMed 
protein kinase C-activating G-protein coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
regulation of sensory perception of pain IDA
Inferred from Direct Assay
more info
PubMed 
release of cytochrome c from mitochondria IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
axon ISO
Inferred from Sequence Orthology
more info
 
axon ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
axon hillock IDA
Inferred from Direct Assay
more info
PubMed 
axon initial segment IDA
Inferred from Direct Assay
more info
PubMed 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region NAS
Non-traceable Author Statement
more info
PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
perikaryon IDA
Inferred from Direct Assay
more info
PubMed 
terminal bouton IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
cholecystokinin
Names
cholecystokinin

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012829.2NP_036961.1  cholecystokinin preproprotein

    See proteins identical to NP_036961.1

    Status: VALIDATED

    Source sequence(s)
    AABR07071762
    UniProtKB/Swiss-Prot
    P01355
    Related
    ENSRNOP00000026159, ENSRNOT00000026159
    Conserved Domains (1) summary
    pfam00918
    Location:2115
    Blast Score: 308
    Gastrin; Gastrin/cholecystokinin family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 

    Range
    130120524..130127295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006244070.2XP_006244132.1  

    Conserved Domains (1) summary
    pfam00918
    Location:4141
    Blast Score: 288
    Gastrin; Gastrin/cholecystokinin family

Alternate Rn_Celera

Genomic

  1. AC_000076.1 

    Range
    120288523..120295093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)