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    Pparg peroxisome proliferator-activated receptor gamma [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25664, updated on 2-Aug-2015
    Official Symbol
    Ppargprovided by RGD
    Official Full Name
    peroxisome proliferator-activated receptor gammaprovided by RGD
    Primary source
    RGD:3371
    See related
    Ensembl:ENSRNOG00000008839
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Summary
    ligand-activated transcription factor; mediates expression of genes involved in lipid metabolism [RGD, Feb 2006]
    Orthologs
    See Pparg in MapViewer
    Location:
    4q42
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    105 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (147274057..147399383)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (210562928..210688585)

    Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene synapsin II Neighboring gene hypothetical LOC100365210 Neighboring gene tubulin alpha-1C chain-like Neighboring gene tissue inhibitor of metalloproteinase 4 Neighboring gene TSEN2 tRNA splicing endonuclease subunit Neighboring gene MKRN2 opposite strand

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • AMPK signaling pathway, organism-specific biosystem (from KEGG)
      AMPK signaling pathway, organism-specific biosystemAMP-activated protein kinase (AMPK) is a serine threonine kinase that is highly conserved through evolution. AMPK system acts as a sensor of cellular energy status. It is activated by increases in th...
    • AMPK signaling pathway, conserved biosystem (from KEGG)
      AMPK signaling pathway, conserved biosystemAMP-activated protein kinase (AMPK) is a serine threonine kinase that is highly conserved through evolution. AMPK system acts as a sensor of cellular energy status. It is activated by increases in th...
    • Adipogenesis, organism-specific biosystem (from WikiPathways)
      Adipogenesis, organism-specific biosystemThe different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, compo...
    • Developmental Biology, organism-specific biosystem (from REACTOME)
      Developmental Biology, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Gene Expression, organism-specific biosystem (from REACTOME)
      Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
      Generic Transcription Pathway, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Huntington's disease, organism-specific biosystem (from KEGG)
      Huntington's disease, organism-specific biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
    • Huntington's disease, conserved biosystem (from KEGG)
      Huntington's disease, conserved biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
    • Nuclear Receptor transcription pathway, organism-specific biosystem (from REACTOME)
      Nuclear Receptor transcription pathway, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Nuclear Receptors, organism-specific biosystem (from WikiPathways)
      Nuclear Receptors, organism-specific biosystemNuclear receptors are a class of proteins found within the interior of cells that are responsible for sensing the presence of steroid and thyroid hormones and certain other molecules. In response, th...
    • Nuclear receptors in lipid metabolism and toxicity, organism-specific biosystem (from WikiPathways)
      Nuclear receptors in lipid metabolism and toxicity, organism-specific biosystemNuclear receptors are transcription factors that are activated upon binding to its ligands. Initially, they had been classified as classic endocrine nuclear hormone receptors and orphan receptors. Ho...
    • Osteoclast differentiation, organism-specific biosystem (from KEGG)
      Osteoclast differentiation, organism-specific biosystemThe osteoclasts, multinucleared cells originating from the hematopoietic monocyte-macrophage lineage, are responsible for bone resorption. Osteoclastogenesis is mainly regulated by signaling pathways...
    • Osteoclast differentiation, conserved biosystem (from KEGG)
      Osteoclast differentiation, conserved biosystemThe osteoclasts, multinucleared cells originating from the hematopoietic monocyte-macrophage lineage, are responsible for bone resorption. Osteoclastogenesis is mainly regulated by signaling pathways...
    • PPAR signaling pathway, organism-specific biosystem (from KEGG)
      PPAR signaling pathway, organism-specific biosystemPeroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated by fatty acids and their derivatives. PPAR has three subtypes (PPARalpha, beta/delta, and gamma) s...
    • PPAR signaling pathway, conserved biosystem (from KEGG)
      PPAR signaling pathway, conserved biosystemPeroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated by fatty acids and their derivatives. PPAR has three subtypes (PPARalpha, beta/delta, and gamma) s...
    • Pathways in cancer, organism-specific biosystem (from KEGG)
      Pathways in cancer, organism-specific biosystem
      Pathways in cancer
    • Thyroid cancer, organism-specific biosystem (from KEGG)
      Thyroid cancer, organism-specific biosystemThyroid cancer is the most common endocrine malignancy and accounts for the majority of endocrine cancer- related deaths each year. More than 95% of thyroid carcinomas are derived from follicular cel...
    • Thyroid cancer, conserved biosystem (from KEGG)
      Thyroid cancer, conserved biosystemThyroid cancer is the most common endocrine malignancy and accounts for the majority of endocrine cancer- related deaths each year. More than 95% of thyroid carcinomas are derived from follicular cel...
    • Transcriptional misregulation in cancer, organism-specific biosystem (from KEGG)
      Transcriptional misregulation in cancer, organism-specific biosystem
      Transcriptional misregulation in cancer
    • Transcriptional misregulation in cancer, conserved biosystem (from KEGG)
      Transcriptional misregulation in cancer, conserved biosystem
      Transcriptional misregulation in cancer
    • Transcriptional regulation of white adipocyte differentiation, organism-specific biosystem (from REACTOME)
      Transcriptional regulation of white adipocyte differentiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II regulatory region DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II regulatory region DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    activating transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
     
    activating transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    alpha-actinin binding IEA
    Inferred from Electronic Annotation
    more info
     
    alpha-actinin binding ISO
    Inferred from Sequence Orthology
    more info
     
    arachidonic acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    core promoter sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    core promoter sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    drug binding IEA
    Inferred from Electronic Annotation
    more info
     
    drug binding ISO
    Inferred from Sequence Orthology
    more info
     
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    estrogen receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ligand-dependent nuclear receptor transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    ligand-dependent nuclear receptor transcription coactivator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein phosphatase binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    retinoid X receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    retinoid X receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    steroid hormone receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor activity, sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor activity, sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription regulatory region DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription regulatory region DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    brown fat cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    brown fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    cell fate commitment ISO
    Inferred from Sequence Orthology
    more info
     
    cell maturation IEA
    Inferred from Electronic Annotation
    more info
     
    cell maturation ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to hyperoxia IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to insulin stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to insulin stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to lithium ion IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to lithium ion ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to organic cyclic compound ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to prostaglandin E stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to prostaglandin stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to retinoic acid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to vitamin E IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    diet induced thermogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    diet induced thermogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    epithelial cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    epithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    fatty acid metabolic process TAS
    Traceable Author Statement
    more info
    PubMed 
    fatty acid oxidation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glucose homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    glucose homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    heart development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    lipoprotein transport IEA
    Inferred from Electronic Annotation
    more info
     
    lipoprotein transport ISO
    Inferred from Sequence Orthology
    more info
     
    long-chain fatty acid transport IEA
    Inferred from Electronic Annotation
    more info
     
    long-chain fatty acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    low-density lipoprotein particle receptor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    low-density lipoprotein particle receptor biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    monocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    monocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of acute inflammatory response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cell growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cellular response to insulin stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cholesterol storage IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cholesterol storage ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of collagen biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cytokine production ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of interferon-gamma-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of interferon-gamma-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of macrophage derived foam cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of pancreatic stellate cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of peptide hormone secretion ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of receptor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of receptor biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of sequestering of triglyceride IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of sequestering of triglyceride ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of smooth muscle cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of smooth muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of telomerase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    organ regeneration IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    peroxisome proliferator activated receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    peroxisome proliferator activated receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    placenta development IEA
    Inferred from Electronic Annotation
    more info
     
    placenta development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of fat cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of fatty acid oxidation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of oligodendrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of phagocytosis, engulfment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of sequence-specific DNA binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of sequence-specific DNA binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of blood pressure IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of blood pressure ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of circadian rhythm ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of circadian rhythm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of fat cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription from RNA polymerase II promoter IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription involved in cell fate commitment ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription involved in cell fate commitment ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    response to caffeine IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to cold IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to dietary excess ISO
    Inferred from Sequence Orthology
    more info
     
    response to diuretic IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to drug IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to estrogen IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to food ISO
    Inferred from Sequence Orthology
    more info
     
    response to immobilization stress IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to light stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    response to lipid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to lipid ISO
    Inferred from Sequence Orthology
    more info
     
    response to low-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
     
    response to low-density lipoprotein particle ISO
    Inferred from Sequence Orthology
    more info
     
    response to mechanical stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to metformin IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to organic cyclic compound IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to organic substance IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to retinoic acid ISO
    Inferred from Sequence Orthology
    more info
     
    response to retinoic acid ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to starvation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to vitamin A IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    rhythmic process IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    steroid hormone mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    transcription from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
     
    transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    white fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    white fat cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    RNA polymerase II transcription factor complex IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II transcription factor complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    peroxisome proliferator-activated receptor gamma
    Names
    PPAR-gamma
    nuclear receptor subfamily 1 group C member 3
    peroxisome proliferator activated receptor gamma
    peroxisome proliferator activator receptor, gamma

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145366.1NP_001138838.1  peroxisome proliferator-activated receptor gamma isoform 2

      See identical proteins and their annotated locations for NP_001138838.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. Both variants 2 and 3 encode the same protein.
      Source sequence(s)
      AC094445, AC136055
      UniProtKB/Swiss-Prot
      O88275
      Related
      ENSRNOP00000045012, ENSRNOT00000051858
      Conserved Domains (3) summary
      cd06932
      Location:207474
      NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
      cd06965
      Location:108191
      NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
      pfam12577
      Location:178
      PPARgamma_N; PPAR gamma N-terminal region
    2. NM_001145367.1NP_001138839.1  peroxisome proliferator-activated receptor gamma isoform 2

      See identical proteins and their annotated locations for NP_001138839.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. Both variants 2 and 3 encode the same protein.
      Source sequence(s)
      AC094445, AC136055
      UniProtKB/Swiss-Prot
      O88275
      Related
      ENSRNOP00000073235, ENSRNOT00000082969
      Conserved Domains (3) summary
      cd06932
      Location:207474
      NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
      cd06965
      Location:108191
      NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
      pfam12577
      Location:178
      PPARgamma_N; PPAR gamma N-terminal region
    3. NM_013124.3NP_037256.1  peroxisome proliferator-activated receptor gamma isoform 1

      See identical proteins and their annotated locations for NP_037256.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1)
      Source sequence(s)
      AC094445, AC136055
      UniProtKB/Swiss-Prot
      O88275
      Related
      ENSRNOP00000012137, ENSRNOT00000012137
      Conserved Domains (3) summary
      cd06932
      Location:237504
      NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
      cd06965
      Location:138221
      NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
      pfam12577
      Location:31108
      PPARgamma_N; PPAR gamma N-terminal region

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

      Range
      147274057..147399383
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237009.2XP_006237071.1  

      See identical proteins and their annotated locations for XP_006237071.1

      UniProtKB/Swiss-Prot
      O88275
      Conserved Domains (3) summary
      cd06932
      Location:207474
      NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
      cd06965
      Location:108191
      NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
      pfam12577
      Location:178
      PPARgamma_N; PPAR gamma N-terminal region

    Alternate Rn_Celera

    Genomic

    1. AC_000072.1 Alternate Rn_Celera

      Range
      137316681..137440473
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)