Display Settings:

Format

Send to:

Choose Destination

wg wingless [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34009, updated on 17-Feb-2015
Official Symbol
wgprovided by FlyBase
Official Full Name
winglessprovided by FlyBase
Primary source
FLYBASE:FBgn0004009
Locus tag
Dmel_CG4889
Gene type
protein coding
RNA name
wingless
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Br; CG4889; Dint-1; Dm Wg; Dm-1; Dmel\CG4889; DWint-1; dWnt; DWnt-1; fg; Gla; I; int-1; l(2)02657; l(2)rO727; l(2)wg; Sp; spd; Wg; WG; wgl; wnt; Wnt; WNT; Wnt-1; Wnt/Wg; wnt1; Wnt1
See wg in MapViewer
Location:
27F1-27F1; 2-21.9 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.01 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7307159..7316265)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7307159..7316265)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene CG13786 gene product from transcript CG13786-RB Neighboring gene CG31909 gene product from transcript CG31909-RC Neighboring gene Wnt oncogene analog 4 Neighboring gene ncRNA Neighboring gene Wnt oncogene analog 6

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
Notch binding TAS
Traceable Author Statement
more info
PubMed 
extracellular matrix binding IDA
Inferred from Direct Assay
more info
PubMed 
frizzled binding IPI
Inferred from Physical Interaction
more info
PubMed 
frizzled-2 binding IDA
Inferred from Direct Assay
more info
PubMed 
frizzled-2 binding IGI
Inferred from Genetic Interaction
more info
PubMed 
frizzled-2 binding IPI
Inferred from Physical Interaction
more info
PubMed 
glycosaminoglycan binding IDA
Inferred from Direct Assay
more info
PubMed 
heparan sulfate proteoglycan binding IPI
Inferred from Physical Interaction
more info
PubMed 
morphogen activity TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
receptor binding NAS
Non-traceable Author Statement
more info
 
Process Evidence Code Pubs
Malpighian tubule bud morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Malpighian tubule tip cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Wnt signaling pathway NAS
Non-traceable Author Statement
more info
 
Wnt signaling pathway, calcium modulating pathway IDA
Inferred from Direct Assay
more info
PubMed 
Wnt signaling pathway, calcium modulating pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
actin filament bundle assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
anterior head segmentation TAS
Traceable Author Statement
more info
PubMed 
anterior/posterior axis specification, embryo NAS
Non-traceable Author Statement
more info
PubMed 
anterior/posterior axis specification, embryo TAS
Traceable Author Statement
more info
PubMed 
anterior/posterior pattern specification, imaginal disc IMP
Inferred from Mutant Phenotype
more info
PubMed 
axis specification IBA
Inferred from Biological aspect of Ancestor
more info
 
branch fusion, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
branching morphogenesis of an epithelial tube IMP
Inferred from Mutant Phenotype
more info
PubMed 
canonical Wnt signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
canonical Wnt signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
cardioblast differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
compound eye development TAS
Traceable Author Statement
more info
PubMed 
compound eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cuticle pattern formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
determination of genital disc primordium IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal closure IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal closure, elongation of leading edge cells IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal/ventral pattern formation, imaginal disc IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal/ventral pattern formation, imaginal disc TAS
Traceable Author Statement
more info
PubMed 
ectoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
epidermis development IMP
Inferred from Mutant Phenotype
more info
PubMed 
epithelial cell proliferation involved in Malpighian tubule morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
epithelial cell type specification, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
filopodium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
genital disc anterior/posterior pattern formation IEP
Inferred from Expression Pattern
more info
PubMed 
genital disc development TAS
Traceable Author Statement
more info
PubMed 
genital disc sexually dimorphic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
heart formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
hindgut morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc development IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc growth TAS
Traceable Author Statement
more info
PubMed 
imaginal disc pattern formation TAS
Traceable Author Statement
more info
PubMed 
imaginal disc-derived wing morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
instar larval development TAS
Traceable Author Statement
more info
PubMed 
labial disc development IMP
Inferred from Mutant Phenotype
more info
PubMed 
lamellipodium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
larval lymph gland hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
larval visceral muscle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
leg disc proximal/distal pattern formation NAS
Non-traceable Author Statement
more info
PubMed 
leg disc proximal/distal pattern formation TAS
Traceable Author Statement
more info
PubMed 
long-term memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
lymph gland crystal cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
lymph gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mesoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mesoderm morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
midbrain-hindbrain boundary development IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of DNA endoreduplication IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of apoptotic process TAS
Traceable Author Statement
more info
PubMed 
negative regulation of cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of fat cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of heart induction by canonical Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of hemocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of phosphorylation NAS
Non-traceable Author Statement
more info
 
negative regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuroblast development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ommatidial rotation TAS
Traceable Author Statement
more info
PubMed 
ovarian follicle cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
pericardial nephrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of compound eye retinal cell programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of crystal cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of stem cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
posterior Malpighian tubule development IMP
Inferred from Mutant Phenotype
more info
PubMed 
posterior head segmentation TAS
Traceable Author Statement
more info
PubMed 
proboscis development IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell proliferation NAS
Non-traceable Author Statement
more info
PubMed 
regulation of compound eye pigmentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of imaginal disc-derived wing size IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mitotic cell cycle TAS
Traceable Author Statement
more info
PubMed 
regulation of stem cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
segment polarity determination IMP
Inferred from Mutant Phenotype
more info
PubMed 
segment polarity determination TAS
Traceable Author Statement
more info
PubMed 
sensory organ development TAS
Traceable Author Statement
more info
PubMed 
somatic stem cell maintenance IBA
Inferred from Biological aspect of Ancestor
more info
 
spiracle morphogenesis, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
synapse organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic growth at neuromuscular junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
trunk segmentation TAS
Traceable Author Statement
more info
PubMed 
ventral cord development TAS
Traceable Author Statement
more info
PubMed 
ventral midline development IMP
Inferred from Mutant Phenotype
more info
PubMed 
wing cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
wing disc development IGI
Inferred from Genetic Interaction
more info
PubMed 
wing disc dorsal/ventral pattern formation TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic membrane-bounded vesicle NAS
Non-traceable Author Statement
more info
PubMed 
colocalizes_with early endosome IDA
Inferred from Direct Assay
more info
PubMed 
endocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region NAS
Non-traceable Author Statement
more info
 
extracellular region TAS
Traceable Author Statement
more info
PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with late endosome IDA
Inferred from Direct Assay
more info
PubMed 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
multivesicular body IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
terminal bouton IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
CG4889 gene product from transcript CG4889-RA
Names
CG4889-PA
Wnt-1
bristled
complementation group I
flag
glazed
spade
sternopleural
wg-PA
wingless

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7307159..7316265
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078778.5NP_523502.1  wingless [Drosophila melanogaster]

    See proteins identical to NP_523502.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    I1WYH9
    UniProtKB/Swiss-Prot
    P09615
    Related
    FBpp0079060, FBtr0079432
    Conserved Domains (1) summary
    pfam00110
    Location:64468
    wnt; wnt family