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    pha-4 Defective pharyngeal development protein 4 [ Caenorhabditis elegans ]

    Gene ID: 180357, updated on 17-Sep-2016
    Gene symbol
    pha-4
    Gene description
    Defective pharyngeal development protein 4
    Primary source
    WormBase:WBGene00004013
    Locus tag
    CELE_F38A6.1
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    See pha-4 in Map Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (20753052..20759680)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DNaJ domain (prokaryotic heat shock protein) Neighboring gene Serpentine Receptor, class XA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Echinoderm microtubule-associated protein-like elp-1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Longevity regulating pathway - multiple species, organism-specific biosystem (from KEGG)
      Longevity regulating pathway - multiple species, organism-specific biosystemAging is a complex process of accumulation of molecular, cellular, and organ damage, leading to loss of function and increased vulnerability to disease and death. Despite the complexity of aging, rec...
    • Longevity regulating pathway - multiple species, conserved biosystem (from KEGG)
      Longevity regulating pathway - multiple species, conserved biosystemAging is a complex process of accumulation of molecular, cellular, and organ damage, leading to loss of function and increased vulnerability to disease and death. Despite the complexity of aging, rec...
    • Longevity regulating pathway - worm, organism-specific biosystem (from KEGG)
      Longevity regulating pathway - worm, organism-specific biosystemThe nematode Caenorhabditis elegans has proven to be a very useful tool for studying the genetics of longevity due to its simple biology. Over 70 genes have been found to influence lifespan in this w...
    • Longevity regulating pathway - worm, conserved biosystem (from KEGG)
      Longevity regulating pathway - worm, conserved biosystemThe nematode Caenorhabditis elegans has proven to be a very useful tool for studying the genetics of longevity due to its simple biology. Over 70 genes have been found to influence lifespan in this w...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II transcription factor activity, sequence-specific DNA binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor activity, sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    autophagy IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell fate specification involved in pattern specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    determination of adult lifespan IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    determination of adult lifespan IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    embryo development ending in birth or egg hatching IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    embryonic morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    gonad development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    hermaphrodite genitalia development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    locomotion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    nematode larval development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    pharynx development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    pharynx development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of macroautophagy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of multicellular organism growth IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    reproduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    response to sodium arsenite IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Defective pharyngeal development protein 4
    NP_001041114.1
    • Confirmed by transcript evidence
    NP_001041115.1
    • Confirmed by transcript evidence
    NP_001041116.1
    • Confirmed by transcript evidence

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      20753052..20759680
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047649.2NP_001041114.1  Defective pharyngeal development protein 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041114.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q17381
      Conserved Domains (1) summary
      smart00339
      Location:236324
      FH; FORKHEAD
    2. NM_001047650.2NP_001041115.1  Defective pharyngeal development protein 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041115.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q17381
      Conserved Domains (1) summary
      smart00339
      Location:172260
      FH; FORKHEAD
    3. NM_001047651.3NP_001041116.1  Defective pharyngeal development protein 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041116.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q17381
      Conserved Domains (1) summary
      smart00339
      Location:141229
      FH; FORKHEAD
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