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MMP13 matrix metallopeptidase 13 (collagenase 3) [ Bos taurus (cattle) ]

Gene ID: 281914, updated on 18-Apr-2015
Gene symbol
MMP13
Gene description
matrix metallopeptidase 13 (collagenase 3)
See related
BGD:BT10004; Ensembl:ENSBTAG00000015059
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
See MMP13 in MapViewer
Location:
chromosome: 15
Exon count:
10
Annotation release Status Assembly Chr Location
104 current Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 15 AC_000172.1 (5912037..5922736)

Chromosome 15 - AC_000172.1Genomic Context describing neighboring genes Neighboring gene DCN1, defective in cullin neddylation 1, domain containing 5 Neighboring gene ATP-dependent RNA helicase DDX19B pseudogene Neighboring gene 60S ribosomal protein L23a-like Neighboring gene matrix metallopeptidase 12 (macrophage elastase)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
collagen binding ISS
Inferred from Sequence or Structural Similarity
more info
 
metalloendopeptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
bone morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
collagen catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular matrix disassembly ISS
Inferred from Sequence or Structural Similarity
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
proteinaceous extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
collagenase 3
Names
collagenase 3
MMP-13
matrix metalloproteinase 13 (collagenase 3)
matrix metalloproteinase-13
NP_776814.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174389.2NP_776814.1  collagenase 3 precursor

    See identical proteins and their annotated locations for NP_776814.1

    Status: PROVISIONAL

    Source sequence(s)
    AF072685
    UniProtKB/Swiss-Prot
    O77656
    Related
    ENSBTAP00000020045, ENSBTAT00000020045
    Conserved Domains (4) summary
    cd00094
    Location:281471
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:112267
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam00413
    Location:112267
    Peptidase_M10; Matrixin
    pfam01471
    Location:3291
    PG_binding_1; Putative peptidoglycan binding domain

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_taurus_UMD_3.1.1 Primary Assembly

Genomic

  1. AC_000172.1 Reference Bos_taurus_UMD_3.1.1 Primary Assembly

    Range
    5912037..5922736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Btau_4.6.1

Genomic

  1. NC_007313.5 Alternate Btau_4.6.1

    Range
    4611283..4621971
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)