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Hadh hydroxyacyl-Coenzyme A dehydrogenase [ Mus musculus (house mouse) ]

Gene ID: 15107, updated on 20-Feb-2015
Official Symbol
Hadhprovided by MGI
Official Full Name
hydroxyacyl-Coenzyme A dehydrogenaseprovided by MGI
Primary source
MGI:MGI:96009
See related
Ensembl:ENSMUSG00000027984; Vega:OTTMUSG00000028850
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HCDH; Schad; Hadhsc; AA409008; AU019341; AW742602
Orthologs
See Hadh in MapViewer
Location:
3; 3 G3
Exon count:
8
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (131233419..131272101, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36603 Neighboring gene lymphoid enhancer binding factor 1 Neighboring gene TatD DNase domain containing 2 pseudogene Neighboring gene uncharacterized LOC100503594 Neighboring gene cytochrome P450, family 2, subfamily u, polypeptide 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
3-hydroxyacyl-CoA dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
3-hydroxyacyl-CoA dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
NAD+ binding IEA
Inferred from Electronic Annotation
more info
 
coenzyme binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
fatty acid beta-oxidation ISO
Inferred from Sequence Orthology
more info
 
fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of insulin secretion ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IDA
Inferred from Direct Assay
more info
PubMed 
response to activity ISO
Inferred from Sequence Orthology
more info
 
response to drug ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
Names
hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain
hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase
medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase
short chain 3-hydroxyacyl-CoA dehydrogenase
short-chain 3-hydroxyacyl-CoA dehydrogenase
NP_032238.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008212.4NP_032238.2  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor

    See proteins identical to NP_032238.2

    Status: VALIDATED

    Source sequence(s)
    AC123634, AI845880, AK132260, AK148486
    Consensus CDS
    CCDS38640.1
    UniProtKB/Swiss-Prot
    Q61425
    Related
    ENSMUSP00000029610, OTTMUSP00000036612, ENSMUST00000029610, OTTMUST00000071450
    Conserved Domains (3) summary
    COG1250
    Location:27313
    FadB; 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]
    pfam00725
    Location:216313
    3HCDH; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
    pfam02737
    Location:29214
    3HCDH_N; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    131233419..131272101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    137754691..137793317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)