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    PIN1 auxin efflux carrier component 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843693, updated on 27-Jun-2015
    Gene symbol
    PIN1
    Gene description
    auxin efflux carrier component 1
    Primary source
    TAIR:AT1G73590
    Locus tag
    AT1G73590
    Gene type
    protein coding
    RNA name
    auxin efflux carrier component 1
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA PIN-FORMED 1; ATPIN1; F6D5.2; F6D5_2; PIN-FORMED 1; PIN1
    Summary
    Encodes an auxin efflux carrier involved in shoot and root development. It is involved in the maintenance of embryonic auxin gradients. Loss of function severely affects organ initiation, pin1 mutants are characterised by an inflorescence meristem that does not initiate any flowers, resulting in the formation of a naked inflorescence stem. PIN1 is involved in the determination of leaf shape by actively promoting development of leaf margin serrations. In roots, the protein mainly resides at the basal end of the vascular cells, but weak signals can be detected in the epidermis and the cortex. Expression levels and polarity of this auxin efflux carrier change during primordium development suggesting that cycles of auxin build-up and depletion accompany, and may direct, different stages of primordium development. PIN1 action on plant development does not strictly require function of PGP1 and PGP19 proteins.
    See PIN1 in MapViewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (27659673..27663178)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene HCP-like superfamily protein Neighboring gene C2 domain-containing protein Neighboring gene putative phosphoethanolamine N-methyltransferase 3 Neighboring gene conserved peptide upstream open reading frame 32 Neighboring gene low-molecular-weight cysteine-rich 64

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description
    NM_106017.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    auxin efflux transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    transporter activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    anthocyanin accumulation in tissues in response to UV light RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    auxin efflux IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    auxin homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    auxin polar transport RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    cell wall macromolecule metabolic process RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    cotyledon development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cotyledon morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    determination of bilateral symmetry RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    flower development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    flower morphogenesis RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    gravitropism IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    inflorescence development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    leaf formation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    leaf morphogenesis RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    leaf shaping IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meristem initiation RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    meristem maintenance RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    negative regulation of biological process RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    nucleotide biosynthetic process RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    organ morphogenesis RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    photomorphogenesis RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    photomorphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    polarity specification of adaxial/abaxial axis RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    regulation of cell size RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    response to auxin RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    response to blue light RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    response to nematode RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    root development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    root development RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    shoot system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    stamen development RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    xylem and phloem pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    xylem and phloem pattern formation RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    xylem development RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    Component Evidence Code Pubs
    apical part of cell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    basal plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    plant-type cell wall IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasmodesma IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    auxin efflux carrier component 1
    NP_177500.1
    • PIN-FORMED 1 (PIN1); FUNCTIONS IN: transporter activity; INVOLVED IN: in 14 processes; LOCATED IN: apical part of cell, plasma membrane, membrane, basal plasma membrane, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT1G70940.1); Has 5945 Blast hits to 4479 proteins in 806 species: Archae - 51; Bacteria - 3010; Metazoa - 784; Fungi - 134; Plants - 814; Viruses - 35; Other Eukaryotes - 1117 (source: NCBI BLink).

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27659673..27663178
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106017.3NP_177500.1  auxin efflux carrier component 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177500.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C6B8
      Conserved Domains (1) summary
      pfam03547
      Location:9173
      Mem_trans; Membrane transport protein