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Sell selectin, lymphocyte [ Mus musculus (house mouse) ]

Gene ID: 20343, updated on 30-Jun-2014
Official Symbol
Sellprovided by MGI
Official Full Name
selectin, lymphocyteprovided by MGI
Primary source
MGI:98279
See related
Ensembl:ENSMUSG00000026581
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; AI528707; L-selectin
See Sell in Epigenomics, MapViewer
Location:
1 H2.2; 1 71.37 cM
Exon count :
10
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 1 NC_000067.6 (164061813..164080785)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene methyltransferase like 18 Neighboring gene selectin, endothelial cell Neighboring gene selectin, platelet Neighboring gene predicted gene 16548 Neighboring gene coagulation factor V

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
cell adhesion molecule binding IPI
Inferred from Physical Interaction
more info
PubMed 
glycolipid binding ISO
Inferred from Sequence Orthology
more info
 
protease binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
positive regulation of neutrophil chemotaxis ISO
Inferred from Sequence Orthology
more info
 
regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
response to ATP IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cell surface IDA
Inferred from Direct Assay
more info
 
cell surface ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
L-selectin
Names
L-selectin
LAM-1
LECAM1
lymphocyte antigen 22
lymph node homing receptor
leukocyte adhesion molecule 1
CD62 antigen-like family member L
lymphocyte surface MEL-14 antigen
leukocyte-endothelial cell adhesion molecule 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164059.1NP_001157531.1  L-selectin isoform 2 precursor

    See proteins identical to NP_001157531.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC110499
    Consensus CDS
    CCDS48421.1
    UniProtKB/TrEMBL
    Q3TCF3
    Related
    ENSMUSP00000095099, ENSMUST00000097491
    Conserved Domains (2) summary
    cd00033
    Location:161219
    Blast Score: 141
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cl02432
    Location:39157
    Blast Score: 383
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  2. NM_011346.2NP_035476.1  L-selectin isoform 1 precursor

    See proteins identical to NP_035476.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AA182222, AK137509, BY210690
    Consensus CDS
    CCDS35753.1
    UniProtKB/Swiss-Prot
    P18337
    UniProtKB/TrEMBL
    Q3UV83
    Related
    ENSMUSP00000027871, ENSMUST00000027871
    Conserved Domains (3) summary
    cd00033
    Location:197255
    Blast Score: 137
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00054
    Location:160192
    Blast Score: 82
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cl02432
    Location:39157
    Blast Score: 382
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000067.6 

    Range
    164061813..164080785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496716.1XP_006496779.1  

    See proteins identical to XP_006496779.1

    UniProtKB/TrEMBL
    B1B507
    Conserved Domains (3) summary
    cd00033
    Location:197255
    Blast Score: 137
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd03592
    Location:39157
    Blast Score: 387
    CLECT_selectins_like; C-type lectin-like domain (CTLD) of the type found in the type 1 transmembrane proteins: P(platlet)-, E(endothelial)-, and L(leukocyte)- selectins (sels)
    cd00054
    Location:160192
    Blast Score: 83
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
  2. XM_006496717.1XP_006496780.1  

    See proteins identical to XP_006496780.1

    UniProtKB/TrEMBL
    B1B506
    Conserved Domains (3) summary
    cd00033
    Location:197255
    Blast Score: 138
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd03592
    Location:39157
    Blast Score: 386
    CLECT_selectins_like; C-type lectin-like domain (CTLD) of the type found in the type 1 transmembrane proteins: P(platlet)-, E(endothelial)-, and L(leukocyte)- selectins (sels)
    cd00054
    Location:160192
    Blast Score: 83
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
  3. XM_006496718.1XP_006496781.1  

    Conserved Domains (3) summary
    cd00033
    Location:197255
    Blast Score: 139
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00054
    Location:160192
    Blast Score: 85
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cl02432
    Location:39157
    Blast Score: 380
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

Alternate Mm_Celera

Genomic

  1. AC_000023.1 

    Range
    166503711..166522465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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