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Bcl2l1 BCL2-like 1 [ Mus musculus (house mouse) ]

Gene ID: 12048, updated on 21-Sep-2014
Official Symbol
Bcl2l1provided by MGI
Official Full Name
BCL2-like 1provided by MGI
Primary source
MGI:MGI:88139
Locus tag
RP23-106A3.4
See related
Ensembl:ENSMUSG00000007659; Vega:OTTMUSG00000015815
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BclX; Bcl2l; bcl-x; Bcl-XL; Bcl(X)L; bcl2-L-1
Summary
This gene encodes a member of the Bcl-2 family of apoptosis regulators. The encoded protein is localized to the inner and outer mitochondrial membranes and regulates the programmed cell death pathway during development and tissue homeostasis. This protein binds to voltage-dependent anion channels in the outer mitochondrial membrane to facilitate the uptake of calcium ions. Mice embryos lacking this gene survived for two weeks and exhibited cell death of immature hematopoietic cells and neurons. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jan 2014]
See Bcl2l1 in Epigenomics, MapViewer
Location:
2 H1; 2 75.41 cM
Exon count:
5
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 2 NC_000068.7 (152780668..152832581, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102634484 Neighboring gene uncharacterized LOC102634403 Neighboring gene cytochrome c oxidase subunit IV isoform 2 Neighboring gene 60S ribosomal protein L39-like Neighboring gene TPX2, microtubule-associated protein homolog (Xenopus laevis) Neighboring gene microRNA mir-5622 Neighboring gene myosin, light polypeptide kinase 2, skeletal muscle

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Amyotrophic lateral sclerosis (ALS), organism-specific biosystem (from KEGG)
    Amyotrophic lateral sclerosis (ALS), organism-specific biosystemAmyotrophic lateral sclerosis (ALS) is a progressive, lethal, degenerative disorder of motor neurons. The hallmark of this disease is the selective death of motor neurons in the brain and spinal cord...
  • Amyotrophic lateral sclerosis (ALS), conserved biosystem (from KEGG)
    Amyotrophic lateral sclerosis (ALS), conserved biosystemAmyotrophic lateral sclerosis (ALS) is a progressive, lethal, degenerative disorder of motor neurons. The hallmark of this disease is the selective death of motor neurons in the brain and spinal cord...
  • Apoptosis, organism-specific biosystem (from WikiPathways)
    Apoptosis, organism-specific biosystemApoptosis is a distinct form of cell death that is functionally and morphologically different from necrosis. Nuclear chromatin condensation, cytoplasmic shrinking, dilated endoplasmic reticulum, and ...
  • Apoptosis, organism-specific biosystem (from KEGG)
    Apoptosis, organism-specific biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
  • Apoptosis, conserved biosystem (from KEGG)
    Apoptosis, conserved biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
  • Apoptosis, organism-specific biosystem (from REACTOME)
    Apoptosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Apoptosis signaling pathway, organism-specific biosystem (from LIPID MAPS)
    Apoptosis signaling pathway, organism-specific biosystem
    Apoptosis signaling pathway
  • BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members, organism-specific biosystem (from REACTOME)
    BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Chronic myeloid leukemia, organism-specific biosystem (from KEGG)
    Chronic myeloid leukemia, organism-specific biosystemChronic myelogenous leukemia (CML) originates in a pluripotent hematopoetic stem cell of the bone marrow and is characterized by greatly increased numbers of granulocytes in the blood. Myeloid and ot...
  • Chronic myeloid leukemia, conserved biosystem (from KEGG)
    Chronic myeloid leukemia, conserved biosystemChronic myelogenous leukemia (CML) originates in a pluripotent hematopoetic stem cell of the bone marrow and is characterized by greatly increased numbers of granulocytes in the blood. Myeloid and ot...
  • HTLV-I infection, organism-specific biosystem (from KEGG)
    HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • HTLV-I infection, conserved biosystem (from KEGG)
    HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • IL-3 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    IL-3 Signaling Pathway, organism-specific biosystemInterleukin-3 belongs to a family of cytokines, which includes IL-5 and GM-CSF. It signals through a receptor complex comprising of an IL-3 specific IL-3 receptor alpha subunit (IL3RA) and a common b...
  • IL-4 signaling Pathway, organism-specific biosystem (from WikiPathways)
    IL-4 signaling Pathway, organism-specific biosystem
    IL-4 signaling Pathway
  • Immune System, organism-specific biosystem (from REACTOME)
    Immune System, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Inflammasomes, organism-specific biosystem (from REACTOME)
    Inflammasomes, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Innate Immune System, organism-specific biosystem (from REACTOME)
    Innate Immune System, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Intrinsic Pathway for Apoptosis, organism-specific biosystem (from REACTOME)
    Intrinsic Pathway for Apoptosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
    Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
  • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
    Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
  • NF-kappa B signaling pathway, organism-specific biosystem (from KEGG)
    NF-kappa B signaling pathway, organism-specific biosystemNuclear factor-kappa B (NF-kappa B) is the generic name of a family of transcription factors that function as dimers and regulate genes involved in immunity, inflammation and cell survival. There are...
  • Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, organism-specific biosystem (from REACTOME)
    Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
    PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
    PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • Pancreatic cancer, organism-specific biosystem (from KEGG)
    Pancreatic cancer, organism-specific biosystemInfiltrating ductal adenocarcinoma is the most common malignancy of the pancreas. When most investigators use the term 'pancreatic cancer' they are referring to pancreatic ductal adenocarcinoma (PDA)...
  • Pancreatic cancer, conserved biosystem (from KEGG)
    Pancreatic cancer, conserved biosystemInfiltrating ductal adenocarcinoma is the most common malignancy of the pancreas. When most investigators use the term 'pancreatic cancer' they are referring to pancreatic ductal adenocarcinoma (PDA)...
  • Pathways in cancer, organism-specific biosystem (from KEGG)
    Pathways in cancer, organism-specific biosystem
    Pathways in cancer
  • Ras signaling pathway, organism-specific biosystem (from KEGG)
    Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...
  • Small cell lung cancer, organism-specific biosystem (from KEGG)
    Small cell lung cancer, organism-specific biosystemLung cancer is a leading cause of cancer death among men and women in industrialized countries. Small cell lung carcinoma (SCLC) is a highly aggressive neoplasm, which accounts for approximately 25% ...
  • Small cell lung cancer, conserved biosystem (from KEGG)
    Small cell lung cancer, conserved biosystemLung cancer is a leading cause of cancer death among men and women in industrialized countries. Small cell lung carcinoma (SCLC) is a highly aggressive neoplasm, which accounts for approximately 25% ...
  • The NLRP1 inflammasome, organism-specific biosystem (from REACTOME)
    The NLRP1 inflammasome, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Toxoplasmosis, organism-specific biosystem (from KEGG)
    Toxoplasmosis, organism-specific biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
  • Toxoplasmosis, conserved biosystem (from KEGG)
    Toxoplasmosis, conserved biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
  • Transcriptional misregulation in cancer, organism-specific biosystem (from KEGG)
    Transcriptional misregulation in cancer, organism-specific biosystem
    Transcriptional misregulation in cancer
  • Transcriptional misregulation in cancer, conserved biosystem (from KEGG)
    Transcriptional misregulation in cancer, conserved biosystem
    Transcriptional misregulation in cancer
  • XPodNet - protein-protein interactions in the podocyte expanded by STRING, organism-specific biosystem (from WikiPathways)
    XPodNet - protein-protein interactions in the podocyte expanded by STRING, organism-specific biosystemXPodNet is a larger version of PodNet. Interactions from STRING database have been added to PodNet to build XPodNet. Hence, not all interactions found in XPodNet do necessarily have to be curated.
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC99998, MGC113803

Gene Ontology Provided by MGI

Function Evidence Code Pubs
BH domain binding ISO
Inferred from Sequence Orthology
more info
 
BH3 domain binding ISO
Inferred from Sequence Orthology
more info
 
MDM2/MDM4 family protein binding ISO
Inferred from Sequence Orthology
more info
 
cysteine-type endopeptidase inhibitor activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
apoptotic process in bone marrow IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
cellular process regulating host cell cycle in response to virus IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to alkaloid IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to amino acid stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to gamma radiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytokinesis ISO
Inferred from Sequence Orthology
more info
 
extrinsic apoptotic signaling pathway in absence of ligand IMP
Inferred from Mutant Phenotype
more info
PubMed 
fertilization IGI
Inferred from Genetic Interaction
more info
PubMed 
germ cell development IGI
Inferred from Genetic Interaction
more info
PubMed 
germ cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
hepatocyte apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
intrinsic apoptotic signaling pathway in response to DNA damage IMP
Inferred from Mutant Phenotype
more info
PubMed 
male gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrion morphogenesis IGI
Inferred from Genetic Interaction
more info
 
mitotic cell cycle checkpoint ISO
Inferred from Sequence Orthology
more info
 
negative regulation of anoikis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of establishment of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
negative regulation of execution phase of apoptosis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of intrinsic apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of neuron apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of release of cytochrome c from mitochondria ISO
Inferred from Sequence Orthology
more info
 
neuron apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
ovarian follicle development IGI
Inferred from Genetic Interaction
more info
PubMed 
ovarian follicle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ovarian follicle development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
regulation of mitochondrial membrane permeability ISO
Inferred from Sequence Orthology
more info
 
regulation of mitochondrial membrane potential ISO
Inferred from Sequence Orthology
more info
 
release of cytochrome c from mitochondria IGI
Inferred from Genetic Interaction
more info
PubMed 
release of cytochrome c from mitochondria ISO
Inferred from Sequence Orthology
more info
 
response to cycloheximide IDA
Inferred from Direct Assay
more info
PubMed 
response to cytokine ISO
Inferred from Sequence Orthology
more info
PubMed 
response to ischemia ISO
Inferred from Sequence Orthology
more info
 
response to radiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to virus IDA
Inferred from Direct Assay
more info
PubMed 
spermatogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
suppression by virus of host apoptotic process ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
Bcl-2 family protein complex ISO
Inferred from Sequence Orthology
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
centrosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
intracellular IMP
Inferred from Mutant Phenotype
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial envelope ISO
Inferred from Sequence Orthology
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
 
mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
synapse IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
bcl-2-like protein 1
Names
bcl-2-like protein 1
apoptosis regulator Bcl-X
B-cell leukemia/lymphoma x
anti-apoptosis regulatory protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289716.1NP_001276645.1  bcl-2-like protein 1 isoform a

    See proteins identical to NP_001276645.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the shorter isoform (a, also known as Bcl-xL; PMID 7607090). Variants 1 through 3 encode the same protein.
    Source sequence(s)
    AK146461, AL731857, BB735910, BY286706
    Consensus CDS
    CCDS16899.1
    UniProtKB/TrEMBL
    Q5HZH3
    UniProtKB/Swiss-Prot
    Q64373
    Conserved Domains (3) summary
    cd06845
    Location:81194
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1233
    bcl-2; apoptosis regulator
  2. NM_001289717.1NP_001276646.1  bcl-2-like protein 1 isoform a

    See proteins identical to NP_001276646.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 through 3 encode the same protein (isoform a, also known as Bcl-xL; PMID 7607090).
    Source sequence(s)
    AL731857
    Consensus CDS
    CCDS16899.1
    UniProtKB/TrEMBL
    Q5HZH3
    UniProtKB/Swiss-Prot
    Q64373
    Conserved Domains (3) summary
    cd06845
    Location:81194
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1233
    bcl-2; apoptosis regulator
  3. NM_001289739.1NP_001276668.1  bcl-2-like protein 1 isoform b

    See proteins identical to NP_001276668.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) has a different 3' structure resulting in a frameshift compared to variant 1. The resulting isoform (b, also known as Bcl-x gamma; PMID 9390687) has a distinct C-terminus and is longer than isoform a.
    Source sequence(s)
    AK146461, AL731857, BY286706, U51277
    UniProtKB/TrEMBL
    O35843
    UniProtKB/TrEMBL
    Q5HZH3
    Conserved Domains (3) summary
    cd06845
    Location:81188
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1188
    bcl-2; apoptosis regulator
  4. NM_009743.5NP_033873.3  bcl-2-like protein 1 isoform a

    See proteins identical to NP_033873.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 through 3 encode the same protein (isoform a, also known as Bcl-xL; PMID 7607090).
    Source sequence(s)
    AL731857, BB735910, BB856100, BC089016
    Consensus CDS
    CCDS16899.1
    UniProtKB/TrEMBL
    Q5HZH3
    UniProtKB/Swiss-Prot
    Q64373
    Related
    ENSMUSP00000007803, OTTMUSP00000016850, ENSMUST00000007803, OTTMUST00000037600
    Conserved Domains (3) summary
    cd06845
    Location:81194
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1233
    bcl-2; apoptosis regulator

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000068.7 

    Range
    152780668..152832581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498612.1XP_006498675.1  

    See proteins identical to XP_006498675.1

    UniProtKB/TrEMBL
    Q5HZH3
    UniProtKB/Swiss-Prot
    Q64373
    Conserved Domains (3) summary
    cd06845
    Location:81194
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1233
    bcl-2; apoptosis regulator
  2. XM_006498610.1XP_006498673.1  

    Conserved Domains (3) summary
    cd06845
    Location:81194
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1233
    bcl-2; apoptosis regulator
  3. XM_006498608.1XP_006498671.1  

    Conserved Domains (3) summary
    cd06845
    Location:81194
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1233
    bcl-2; apoptosis regulator
  4. XM_006498609.1XP_006498672.1  

    See proteins identical to XP_006498672.1

    UniProtKB/TrEMBL
    Q5HZH3
    UniProtKB/Swiss-Prot
    Q64373
    Conserved Domains (3) summary
    cd06845
    Location:81194
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1233
    bcl-2; apoptosis regulator
  5. XM_006498611.1XP_006498674.1  

    See proteins identical to XP_006498674.1

    UniProtKB/TrEMBL
    Q5HZH3
    UniProtKB/Swiss-Prot
    Q64373
    Conserved Domains (3) summary
    cd06845
    Location:81194
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    pfam02180
    Location:127
    BH4; Bcl-2 homology region 4
    TIGR00865
    Location:1233
    bcl-2; apoptosis regulator

RNA

  1. XR_374396.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000024.1 

    Range
    158596643..158647694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)