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E2f8 E2F transcription factor 8 [ Mus musculus (house mouse) ]

Gene ID: 108961, updated on 7-Aug-2014
Official Symbol
E2f8provided by MGI
Official Full Name
E2F transcription factor 8provided by MGI
Primary source
MGI:1922038
See related
Ensembl:ENSMUSG00000046179; Vega:OTTMUSG00000029718
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AA410048; 4432406C08Rik
See E2f8 in Epigenomics, MapViewer
Location:
7 B4; 7
Exon count:
15
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 7 NC_000073.6 (48866429..48882073, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene zinc finger, DHHC domain containing 13 Neighboring gene cysteine and glycine-rich protein 3 Neighboring gene uncharacterized LOC545966 Neighboring gene RAN, member RAS oncogene family pseudogene Neighboring gene uncharacterized LOC102635611 Neighboring gene neuron navigator 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell cycle comprising mitosis without cytokinesis IMP
Inferred from Mutant Phenotype
more info
 
cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
chorionic trophoblast cell differentiation IMP
Inferred from Mutant Phenotype
more info
 
hepatocyte differentiation IMP
Inferred from Mutant Phenotype
more info
 
negative regulation of cytokinesis IMP
Inferred from Mutant Phenotype
more info
 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
placenta development IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of DNA endoreduplication IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
sprouting angiogenesis IMP
Inferred from Mutant Phenotype
more info
 
sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
trophoblast giant cell differentiation IMP
Inferred from Mutant Phenotype
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
transcription factor E2F8
Names
transcription factor E2F8
E2F-8
E2f family member 8

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013368.5NP_001013386.2  transcription factor E2F8

    See proteins identical to NP_001013386.2

    Status: VALIDATED

    Source sequence(s)
    AK084513, AK160240, BX528987
    Consensus CDS
    CCDS39967.1
    UniProtKB/Swiss-Prot
    Q58FA4
    Related
    ENSMUSP00000056778, OTTMUSP00000038213, ENSMUST00000058745, OTTMUST00000073729
    Conserved Domains (1) summary
    pfam02319
    Location:113182
    Blast Score: 250
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000073.6 

    Range
    48866429..48882073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540554.1XP_006540617.1  

    See proteins identical to XP_006540617.1

    UniProtKB/Swiss-Prot
    Q58FA4
    Conserved Domains (1) summary
    pfam02319
    Location:113182
    Blast Score: 250
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
  2. XM_006540553.1XP_006540616.1  

    See proteins identical to XP_006540616.1

    UniProtKB/Swiss-Prot
    Q58FA4
    Related
    ENSMUSP00000112883, OTTMUSP00000038212, ENSMUST00000119223, OTTMUST00000073728
    Conserved Domains (1) summary
    pfam02319
    Location:113182
    Blast Score: 250
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain

Alternate Mm_Celera

Genomic

  1. AC_000029.1 

    Range
    44310478..44325086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)