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Metap2 methionine aminopeptidase 2 [ Mus musculus (house mouse) ]

Gene ID: 56307, updated on 11-Sep-2014
Official Symbol
Metap2provided by MGI
Official Full Name
methionine aminopeptidase 2provided by MGI
Primary source
MGI:1929701
See related
Ensembl:ENSMUSG00000036112; Vega:OTTMUSG00000042658
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p67; Amp2; Mnpep; p67eIF2; AI047573; AL024412; AU014659; 4930584B20Rik; A930035J23Rik
See Metap2 in Epigenomics, MapViewer
Location:
10 C2; 10
Exon count:
13
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 10 NC_000076.6 (93858489..93897090, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene netrin 4 Neighboring gene predicted gene 15915 Neighboring gene farnesyl diphosphate synthetase pseudogene Neighboring gene ubiquitin specific peptidase 44 Neighboring gene microRNA 331 Neighboring gene vezatin, adherens junctions transmembrane protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC102452

Gene Ontology Provided by MGI

Function Evidence Code Pubs
aminopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
metalloexopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
N-terminal protein amino acid modification ISO
Inferred from Sequence Orthology
more info
 
peptidyl-methionine modification ISO
Inferred from Sequence Orthology
more info
 
protein processing ISO
Inferred from Sequence Orthology
more info
 
proteolysis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
methionine aminopeptidase 2
Names
methionine aminopeptidase 2
MAP 2
metAP 2
peptidase M 2
eIF-2-associated p67
initiation factor 2-associated protein (p67)
initiation factor 2-associated 67 kDa glycoprotein
NP_062622.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019648.3NP_062622.1  methionine aminopeptidase 2

    See proteins identical to NP_062622.1

    Status: VALIDATED

    Source sequence(s)
    AC124686, AF434712, AK165301
    Consensus CDS
    CCDS48673.1
    UniProtKB/Swiss-Prot
    O08663
    UniProtKB/TrEMBL
    Q58E65
    Related
    ENSMUSP00000048285, OTTMUSP00000063063, ENSMUST00000047910, OTTMUST00000112328
    Conserved Domains (2) summary
    cd01088
    Location:166474
    MetAP2; Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
    PTZ00053
    Location:107478
    PTZ00053; methionine aminopeptidase 2; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000076.6 

    Range
    93858489..93897090
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513896.1XP_006513959.1  

    See proteins identical to XP_006513959.1

    UniProtKB/Swiss-Prot
    O08663
    UniProtKB/TrEMBL
    Q58E65
    Conserved Domains (2) summary
    cd01088
    Location:166474
    MetAP2; Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
    PTZ00053
    Location:107478
    PTZ00053; methionine aminopeptidase 2; Provisional
  2. XM_006513898.1XP_006513961.1  

    Conserved Domains (2) summary
    cd01088
    Location:165473
    MetAP2; Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
    PTZ00053
    Location:106477
    PTZ00053; methionine aminopeptidase 2; Provisional
  3. XM_006513897.1XP_006513960.1  

    See proteins identical to XP_006513960.1

    UniProtKB/Swiss-Prot
    O08663
    UniProtKB/TrEMBL
    Q58E65
    Related
    ENSMUSP00000138006, OTTMUSP00000063064, ENSMUST00000180840, OTTMUST00000112330
    Conserved Domains (2) summary
    cd01088
    Location:166474
    MetAP2; Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
    PTZ00053
    Location:107478
    PTZ00053; methionine aminopeptidase 2; Provisional

Alternate Mm_Celera

Genomic

  1. AC_000032.1 

    Range
    95828659..95861285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)