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SLAMF1 signaling lymphocytic activation molecule family member 1 [ Homo sapiens (human) ]

Gene ID: 6504, updated on 7-Dec-2014
Official Symbol
SLAMF1provided by HGNC
Official Full Name
signaling lymphocytic activation molecule family member 1provided by HGNC
Primary source
HGNC:HGNC:10903
Locus tag
RP11-528G1.4
See related
HPRD:04603; MIM:603492
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SLAM; CD150; CDw150
See SLAMF1 in Epigenomics, MapViewer
Location:
1q23.3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 1 NC_000001.11 (160609819..160647311, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (160579891..160617081, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene SLAM family member 6 Neighboring gene CD84 molecule Neighboring gene SET pseudogene 9 Neighboring gene CD48 molecule

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association study of treatment refractory schizophrenia in Han Chinese.
NHGRI GWA Catalog
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
NHGRI GWA Catalog
  • Measles, organism-specific biosystem (from KEGG)
    Measles, organism-specific biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
  • Measles, conserved biosystem (from KEGG)
    Measles, conserved biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
antigen binding TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transmembrane signaling receptor activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
lymphocyte activation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell proliferation TAS
Traceable Author Statement
more info
PubMed 
regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
regulation of vesicle fusion IEA
Inferred from Electronic Annotation
more info
 
signal transduction TAS
Traceable Author Statement
more info
PubMed 
viral process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
phagocytic vesicle IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
signaling lymphocytic activation molecule
Names
signaling lymphocytic activation molecule
IPO-3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_003037.3NP_003028.1  signaling lymphocytic activation molecule precursor

    See proteins identical to NP_003028.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein.
    Source sequence(s)
    AL121985, AL138930, BC132792
    Consensus CDS
    CCDS1207.1
    UniProtKB/Swiss-Prot
    Q13291
    Conserved Domains (1) summary
    pfam06214
    Location:1126
    SLAM; Signaling lymphocytic activation molecule (SLAM) protein

RNA

  1. NR_104399.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK304237, AL121985, AL138930
  2. NR_104400.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AL121985, AL138930, BC144498
  3. NR_104401.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AL121985, AL138930, BC144499

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000001.11 

    Range
    160609819..160647311
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005245456.1XP_005245513.1  

    See proteins identical to XP_005245513.1

    UniProtKB/Swiss-Prot
    Q13291
    Conserved Domains (1) summary
    pfam06214
    Location:1126
    SLAM; Signaling lymphocytic activation molecule (SLAM) protein
  2. XM_005245457.1XP_005245514.1  

    Conserved Domains (1) summary
    pfam06214
    Location:1126
    SLAM; Signaling lymphocytic activation molecule (SLAM) protein

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 

    Range
    161974960..162012440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000133.1 

    Range
    131935826..131973295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)