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Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform [ Mus musculus (house mouse) ]

Gene ID: 13026, updated on 17-Mar-2015
Official Symbol
Pcyt1aprovided by MGI
Official Full Name
phosphate cytidylyltransferase 1, choline, alpha isoformprovided by MGI
Primary source
MGI:MGI:88557
See related
Ensembl:ENSMUSG00000005615; Vega:OTTMUSG00000025786
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ctpct; CTalpha; Cctalpha; Cttalpha
Orthologs
See Pcyt1a in MapViewer
Location:
16 B3; 16 22.69 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (32430921..32475065)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (32431007..32475151)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene transmembrane 4 L six family member 19 Neighboring gene calcium-binding protein p22-like Neighboring gene Tctex1 domain containing 2 Neighboring gene solute carrier family 51, alpha subunit Neighboring gene zinc finger, DHHC domain containing 19

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
choline-phosphate cytidylyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
lipid binding ISO
Inferred from Sequence Orthology
more info
 
nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
CDP-choline pathway ISO
Inferred from Sequence Orthology
more info
 
biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
phosphatidylcholine biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylcholine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
glycogen granule IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
choline-phosphate cytidylyltransferase A
Names
choline-phosphate cytidylyltransferase A
CCT A
CCT-alpha
CT A
CTP phosphocholine cytidylyl transferase
CTP:phosphocholine cytidylyltransferase A
CTP:phosphocholine cytidylyltransferase alpha
phosphorylcholine transferase A
NP_001156631.1
NP_001156632.1
NP_034111.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163159.1NP_001156631.1  choline-phosphate cytidylyltransferase A

    See proteins identical to NP_001156631.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
    Source sequence(s)
    AC087556, AK076050
    Consensus CDS
    CCDS28120.1
    UniProtKB/Swiss-Prot
    P49586
    Related
    ENSMUSP00000130056, ENSMUST00000104893
    Conserved Domains (1) summary
    cd02174
    Location:75224
    CCT; CTP:phosphocholine cytidylyltransferase
  2. NM_001163160.1NP_001156632.1  choline-phosphate cytidylyltransferase A

    See proteins identical to NP_001156632.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AC087556, AK076050
    Consensus CDS
    CCDS28120.1
    UniProtKB/Swiss-Prot
    P49586
    Conserved Domains (1) summary
    cd02174
    Location:75224
    CCT; CTP:phosphocholine cytidylyltransferase
  3. NM_009981.4NP_034111.1  choline-phosphate cytidylyltransferase A

    See proteins identical to NP_034111.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AC087556, AK076050, BB642590
    Consensus CDS
    CCDS28120.1
    UniProtKB/Swiss-Prot
    P49586
    Related
    ENSMUSP00000078721, OTTMUSP00000031399, ENSMUST00000079791, OTTMUST00000063507
    Conserved Domains (1) summary
    cd02174
    Location:75224
    CCT; CTP:phosphocholine cytidylyltransferase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    32430921..32475065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    32915098..32958968
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)