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Tyrobp TYRO protein tyrosine kinase binding protein [ Mus musculus (house mouse) ]

Gene ID: 22177, updated on 19-Jul-2014
Official Symbol
Tyrobpprovided by MGI
Official Full Name
TYRO protein tyrosine kinase binding proteinprovided by MGI
Primary source
MGI:1277211
See related
Ensembl:ENSMUSG00000030579
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ly83; DAP12; KARAP
See Tyrobp in Epigenomics, MapViewer
Location:
7 B; 7 17.45 cM
Exon count:
5
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 7 NC_000073.6 (30413788..30417582)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene leucine rich repeat and fibronectin type III domain containing 3 Neighboring gene uncharacterized LOC102634448 Neighboring gene hematopoietic cell signal transducer Neighboring gene nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
receptor binding ISO
Inferred from Sequence Orthology
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
integrin-mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
macrophage activation involved in immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
neutrophil activation involved in immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of osteoclast development IGI
Inferred from Genetic Interaction
more info
 
Component Evidence Code Pubs
cell surface ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
TYRO protein tyrosine kinase-binding protein
Names
TYRO protein tyrosine kinase-binding protein
KAR-associated protein
DNAX-activation protein 12
killer-activating receptor-associated protein
killer cell activating receptor associated protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011662.2NP_035792.1  TYRO protein tyrosine kinase-binding protein precursor

    See proteins identical to NP_035792.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056450
    Consensus CDS
    CCDS21089.1
    UniProtKB/Swiss-Prot
    O54885
    UniProtKB/TrEMBL
    Q3U419
    Related
    ENSMUSP00000032800, ENSMUST00000032800
    Conserved Domains (1) summary
    pfam07213
    Location:2272
    Blast Score: 77
    DAP10; DAP10 membrane protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000073.6 

    Range
    30413788..30417582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000029.1 

    Range
    25005487..25009294
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)