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Endog endonuclease G [ Mus musculus (house mouse) ]

Gene ID: 13804, updated on 19-Jul-2014
Official Symbol
Endogprovided by MGI
Official Full Name
endonuclease Gprovided by MGI
Primary source
MGI:1261433
Locus tag
RP23-315H12.3
See related
Ensembl:ENSMUSG00000015337; Vega:OTTMUSG00000016745
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
See Endog in Epigenomics, MapViewer
Location:
2 B; 2
Exon count:
4
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 2 NC_000068.7 (30171408..30174069)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 (zinc transporter), member 1, pseudogene Neighboring gene uncharacterized LOC102633192 Neighboring gene DNA segment, Chr 2, Wayne State University 81, expressed Neighboring gene cysteine conjugate-beta lyase 1 Neighboring gene uncharacterized LOC102633356 Neighboring gene RIKEN cDNA 1700084E18 gene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Apoptosis, organism-specific biosystem (from KEGG)
    Apoptosis, organism-specific biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
  • Apoptosis, conserved biosystem (from KEGG)
    Apoptosis, conserved biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
  • Apoptosis signaling pathway, organism-specific biosystem (from LIPID MAPS)
    Apoptosis signaling pathway, organism-specific biosystem
    Apoptosis signaling pathway

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
endonuclease activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA catabolic process TAS
Traceable Author Statement
more info
PubMed 
apoptotic DNA fragmentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleic acid phosphodiester bond hydrolysis IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of apoptotic process TAS
Traceable Author Statement
more info
PubMed 
response to antibiotic IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to tumor necrosis factor IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
endonuclease G, mitochondrial
Names
endonuclease G, mitochondrial
endo G

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007931.1NP_031957.1  endonuclease G, mitochondrial precursor

    See proteins identical to NP_031957.1

    Status: PROVISIONAL

    Source sequence(s)
    AB012108
    Consensus CDS
    CCDS15872.1
    UniProtKB/Swiss-Prot
    O08600
    UniProtKB/TrEMBL
    Q3UN47
    Related
    ENSMUSP00000015481, OTTMUSP00000018152, ENSMUST00000015481, OTTMUST00000040620
    Conserved Domains (1) summary
    cd00091
    Location:62279
    Blast Score: 676
    NUC; DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases. They exists as monomers and homodimers.

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000068.7 

    Range
    30171408..30174069
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_374059.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000024.1 

    Range
    29875396..29877941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)