Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    bec-1 BEClin (human autophagy) homolog [ Caenorhabditis elegans ]

    Gene ID: 177345, updated on 5-Jun-2016
    Gene symbol
    bec-1
    Gene description
    BEClin (human autophagy) homolog
    Primary source
    WormBase:WBGene00000247
    Locus tag
    CELE_T19E7.3
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    See bec-1 in Map Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (5661340..5664417, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Protein skinhead-1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    • Homologs of the bec-1 gene: The bec-1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    CVT pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    apoptotic cell clearance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    autophagy IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    autophagy IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cell death IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    cellular response to nitrogen starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cellular response to starvation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dauer larval development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    defense response IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    determination of adult lifespan IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    determination of adult lifespan IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    embryo development ending in birth or egg hatching IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    growth IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    hermaphrodite genitalia development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    late endosome to vacuole transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    lipid storage IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    locomotion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    necrotic cell death IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    negative regulation of vulval development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    nematode larval development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    nematode male tail tip morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of multicellular organism growth IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    programmed cell death IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of multicellular organism growth IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    reproduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic, membrane-bounded vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phosphatidylinositol 3-kinase complex, class III, type I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    phosphatidylinositol 3-kinase complex, class III, type II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    pre-autophagosomal structure IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Names
    BEClin (human autophagy) homolog
    NP_001293684.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class bec
    NP_500844.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class bec

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      5661340..5664417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068443.3NP_500844.1  BEClin (human autophagy) homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500844.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22592
      Conserved Domains (2) summary
      pfam04111
      Location:63368
      APG6; Autophagy protein Apg6
      cl19219
      Location:70149
      DUF342; Protein of unknown function (DUF342)
    2. NM_001306755.1NP_001293684.1  BEClin (human autophagy) homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293684.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22592
      Conserved Domains (1) summary
      pfam04111
      Location:2111
      APG6; Autophagy protein Apg6