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IGJ immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides [ Homo sapiens (human) ]

Gene ID: 3512, updated on 13-Jan-2015
Official Symbol
IGJprovided by HGNC
Official Full Name
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptidesprovided by HGNC
Primary source
HGNC:HGNC:5713
See related
Ensembl:ENSG00000132465; HPRD:00991; MIM:147790; Vega:OTTHUMG00000129909
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JCH; IGCJ
Orthologs
See IGJ in MapViewer
Location:
4q21
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 4 NC_000004.12 (70655541..70676903, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (71521258..71532348, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene ameloblastin (enamel matrix protein) Neighboring gene enamelin Neighboring gene uncharacterized LOC101927297 Neighboring gene UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
IgA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
antigen binding NAS
Non-traceable Author Statement
more info
PubMed 
contributes_to immunoglobulin receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to immunoglobulin receptor binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
contributes_to peptidoglycan binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to phosphatidylcholine binding IDA
Inferred from Direct Assay
more info
PubMed 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
adaptive immune response IDA
Inferred from Direct Assay
more info
PubMed 
antibacterial humoral response IDA
Inferred from Direct Assay
more info
PubMed 
glomerular filtration IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune response NAS
Non-traceable Author Statement
more info
PubMed 
innate immune response IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of protein oligomerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of respiratory burst IDA
Inferred from Direct Assay
more info
PubMed 
retina homeostasis IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
blood microparticle IDA
Inferred from Direct Assay
more info
PubMed 
dimeric IgA immunoglobulin complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
extracellular region NAS
Non-traceable Author Statement
more info
PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular vesicular exosome IDA
Inferred from Direct Assay
more info
PubMed 
NOT hexameric IgM immunoglobulin complex IDA
Inferred from Direct Assay
more info
PubMed 
monomeric IgA immunoglobulin complex IDA
Inferred from Direct Assay
more info
PubMed 
pentameric IgM immunoglobulin complex IDA
Inferred from Direct Assay
more info
PubMed 
secretory IgA immunoglobulin complex IDA
Inferred from Direct Assay
more info
PubMed 
secretory dimeric IgA immunoglobulin complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
immunoglobulin J chain
Names
immunoglobulin J chain
IgJ chain

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144646.3NP_653247.1  immunoglobulin J chain precursor

    See proteins identical to NP_653247.1

    Status: VALIDATED

    Source sequence(s)
    BC038982, BP221304, BP261870, BP418109
    Consensus CDS
    CCDS3545.1
    UniProtKB/Swiss-Prot
    P01591
    Related
    ENSP00000440066, ENST00000543780
    Conserved Domains (1) summary
    pfam15097
    Location:24159
    Ig_J_chain; Immunoglobulin J chain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000004.12 

    Range
    70655541..70676903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006714212.1XP_006714275.1  

    See proteins identical to XP_006714275.1

    UniProtKB/Swiss-Prot
    P01591
    Conserved Domains (1) summary
    pfam15097
    Location:24159
    Ig_J_chain; Immunoglobulin J chain
  2. XM_006714211.1XP_006714274.1  

    See proteins identical to XP_006714274.1

    UniProtKB/Swiss-Prot
    P01591
    Conserved Domains (1) summary
    pfam15097
    Location:24159
    Ig_J_chain; Immunoglobulin J chain

Alternate CHM1_1.1

Genomic

  1. NC_018915.2 

    Range
    71557251..71568341
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000136.1 

    Range
    67325225..67336298
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)