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Slpi secretory leukocyte peptidase inhibitor [ Mus musculus (house mouse) ]

Gene ID: 20568, updated on 7-Aug-2014
Official Symbol
Slpiprovided by MGI
Official Full Name
secretory leukocyte peptidase inhibitorprovided by MGI
Primary source
MGI:109297
Locus tag
RP23-462O16.7
See related
Ensembl:ENSMUSG00000017002; Vega:OTTMUSG00000001167
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
See Slpi in Epigenomics, MapViewer
Location:
2 H; 2
Exon count:
4
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 2 NC_000068.7 (164354070..164356507, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene seminal vesicle secretory protein 6 Neighboring gene seminal vesicle secretory protein 5 Neighboring gene microRNA mir-7678 Neighboring gene matrilin 4 Neighboring gene recombination signal binding protein for immunoglobulin kappa J region-like Neighboring gene syndecan 4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
negative regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of protein binding ISO
Inferred from Sequence Orthology
more info
 
negative regulation of viral genome replication ISO
Inferred from Sequence Orthology
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
colocalizes_with extracellular matrix ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
antileukoproteinase
Names
antileukoproteinase
ALP
secretory leukocyte protease inhibitor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011414.3NP_035544.1  antileukoproteinase precursor

    See proteins identical to NP_035544.1

    Status: PROVISIONAL

    Source sequence(s)
    BC028509
    Consensus CDS
    CCDS17033.1
    UniProtKB/Swiss-Prot
    P97430
    UniProtKB/TrEMBL
    Q548X8
    Related
    ENSMUSP00000104992, OTTMUSP00000001108, ENSMUST00000109367, OTTMUST00000002263
    Conserved Domains (2) summary
    cd00199
    Location:81131
    Blast Score: 107
    WAP; whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of ...
    pfam00095
    Location:5076
    Blast Score: 89
    WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000068.7 

    Range
    164354070..164356507
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000024.1 

    Range
    170287487..170289924
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)