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Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 [ Mus musculus (house mouse) ]

Gene ID: 16522, updated on 18-Mar-2015
Official Symbol
Kcnj6provided by MGI
Official Full Name
potassium inwardly-rectifying channel, subfamily J, member 6provided by MGI
Primary source
MGI:MGI:104781
See related
Ensembl:ENSMUSG00000043301
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
wv; BIR1; GIRK2; KATP2; KCNJ7; Kir3.2; weaver
Orthologs
See Kcnj6 in MapViewer
Location:
16 C4; 16 55.44 cM
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (94748683..94997696, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (94970290..95219303, complement)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105246170 Neighboring gene uncharacterized LOC105246173 Neighboring gene uncharacterized LOC105246171 Neighboring gene predicted gene, 31407 Neighboring gene predicted gene, 31641 Neighboring gene predicted gene, 31754

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein activated inward rectifier potassium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
G-protein alpha-subunit binding ISO
Inferred from Sequence Orthology
more info
 
inward rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 
voltage-gated ion channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
ion transport IEA
Inferred from Electronic Annotation
more info
 
potassium ion import IBA
Inferred from Biological aspect of Ancestor
more info
 
potassium ion transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
potassium ion transport IEA
Inferred from Electronic Annotation
more info
 
regulation of ion transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
thyroid hormone metabolic process IMP
Inferred from Mutant Phenotype
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
axon ISO
Inferred from Sequence Orthology
more info
 
cell surface ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body membrane ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
G protein-activated inward rectifier potassium channel 2
Names
G protein-activated inward rectifier potassium channel 2
GIRK-2
inward rectifier K(+) channel Kir3.2
potassium channel, inwardly rectifying subfamily J member 6
potassium inwardly-rectifying channel J6

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025584.2NP_001020755.1  G protein-activated inward rectifier potassium channel 2 isoform Girk2-1

    See identical proteins and their annotated locations for NP_001020755.1

    Status: VALIDATED

    Source sequence(s)
    AK081109, BB591362
    Consensus CDS
    CCDS37408.1
    UniProtKB/TrEMBL
    Q8C4T8
    Conserved Domains (1) summary
    pfam01007
    Location:59374
    IRK; Inward rectifier potassium channel
  2. NM_001025585.2NP_001020756.1  G protein-activated inward rectifier potassium channel 2 isoform Girk2B

    See identical proteins and their annotated locations for NP_001020756.1

    Status: VALIDATED

    Source sequence(s)
    BB277039, BB591362, D86040
    UniProtKB/Swiss-Prot
    P48542
    Conserved Domains (1) summary
    pfam01007
    Location:59318
    IRK; Inward rectifier potassium channel
  3. NM_001025590.1NP_001020761.1  G protein-activated inward rectifier potassium channel 2 isoform Girk2C

    See identical proteins and their annotated locations for NP_001020761.1

    Status: VALIDATED

    Source sequence(s)
    AC165248, AK015481
    Consensus CDS
    CCDS49921.1
    UniProtKB/Swiss-Prot
    P48542
    Related
    ENSMUSP00000130321, ENSMUST00000165538
    Conserved Domains (1) summary
    pfam01007
    Location:41300
    IRK; Inward rectifier potassium channel
  4. NM_010606.2NP_034736.2  G protein-activated inward rectifier potassium channel 2 isoform Girk2A-1

    See identical proteins and their annotated locations for NP_034736.2

    Status: VALIDATED

    Source sequence(s)
    AB029502, AC165271, AK044218, BB591362
    Consensus CDS
    CCDS37409.1
    UniProtKB/Swiss-Prot
    P48542
    UniProtKB/TrEMBL
    Q0VB45
    UniProtKB/TrEMBL
    Q8C8Y6
    Related
    ENSMUSP00000097108, ENSMUST00000099508
    Conserved Domains (1) summary
    pfam01007
    Location:59374
    IRK; Inward rectifier potassium channel

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    94748683..94997696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246104.1XP_011244406.1  

    See identical proteins and their annotated locations for XP_011244406.1

    Conserved Domains (1) summary
    pfam01007
    Location:41356
    IRK; Inward rectifier potassium channel

Reference GRCm38.p3 129S6/SvEvTac

Genomic

  1. NT_039634.4 Reference GRCm38.p3 129S6/SvEvTac

    Range
    631000..878250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    95836338..96085607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)