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Cxcl10 chemokine (C-X-C motif) ligand 10 [ Mus musculus (house mouse) ]

Gene ID: 15945, updated on 19-Jul-2014
Official Symbol
Cxcl10provided by MGI
Official Full Name
chemokine (C-X-C motif) ligand 10provided by MGI
Primary source
MGI:1352450
See related
Ensembl:ENSMUSG00000034855; Vega:OTTMUSG00000028740
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
See Cxcl10 in Epigenomics, MapViewer
Location:
5 E2; 5 46.57 cM
Exon count:
4
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 5 NC_000071.6 (92346638..92348889, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene SDA1 domain containing 1 Neighboring gene chemokine (C-X-C motif) ligand 9 Neighboring gene ADP-ribosyltransferase 3 Neighboring gene chemokine (C-X-C motif) ligand 11 Neighboring gene CWF19-like 1, cell cycle control pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
CXCR3 chemokine receptor binding ISO
Inferred from Sequence Orthology
more info
 
chemokine activity ISO
Inferred from Sequence Orthology
more info
 
cytokine activity IEA
Inferred from Electronic Annotation
more info
 
heparin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
T cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
cellular response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
chemokine-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
chemotaxis ISO
Inferred from Sequence Orthology
more info
 
defense response to virus IDA
Inferred from Direct Assay
more info
PubMed 
immune response ISO
Inferred from Sequence Orthology
more info
 
inflammatory response IEA
Inferred from Electronic Annotation
more info
 
negative regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of T cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cAMP metabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cAMP-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of leukocyte chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
 
protein secretion ISO
Inferred from Sequence Orthology
more info
 
regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
signal transduction ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region ISO
Inferred from Sequence Orthology
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
C-X-C motif chemokine 10
Names
C-X-C motif chemokine 10
gamma-IP10
interferon activated gene 10
small-inducible cytokine B10
interferon-gamma induced protein CRG-2
interferon-gamma-induced protein CRG-2
10 kDa interferon gamma-induced protein
small inducible cytokine B subfamily (Cys-X-Cys), member 10

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021274.2NP_067249.1  C-X-C motif chemokine 10 precursor

    See proteins identical to NP_067249.1

    Status: VALIDATED

    Source sequence(s)
    BC030067, BY165450
    Consensus CDS
    CCDS39153.1
    UniProtKB/Swiss-Prot
    P17515
    UniProtKB/TrEMBL
    Q548V9
    Related
    ENSMUSP00000047646, OTTMUSP00000036424, ENSMUST00000038816, OTTMUST00000071189
    Conserved Domains (1) summary
    cd00273
    Location:2788
    Blast Score: 167
    Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000071.6 

    Range
    92346638..92348889
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 

    Range
    90490433..90492679
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)