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    dl dorsal [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35047, updated on 10-Sep-2016
    Official Symbol
    dlprovided by FlyBase
    Official Full Name
    dorsalprovided by FlyBase
    Primary source
    FLYBASE:FBgn0260632
    Locus tag
    Dmel_CG6667
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:GressD7; CG6667; d; dL; Dl; DL; Dmel\CG6667; Dor; Dorsal; fs(2)k10816; GSd447; mat(2)dorsal; NFkappaB; REL
    See dl in Map Viewer
    Location:
    36C8-36C9; 2-52.9 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.07 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (17436830..17450364, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (17436830..17450364, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene CG5043 gene product from transcript CG5043-RA Neighboring gene CG33928 gene product from transcript CG33928-RA Neighboring gene ncRNA Neighboring gene CG5050 gene product from transcript CG5050-RA Neighboring gene CG6639 gene product from transcript CG6639-RA

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    Toll signaling pathway NAS
    Non-traceable Author Statement
    more info
     
    Toll signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    anterior/posterior pattern specification TAS
    Traceable Author Statement
    more info
    PubMed 
    defense response NAS
    Non-traceable Author Statement
    more info
     
    defense response TAS
    Traceable Author Statement
    more info
    PubMed 
    dorsal/ventral axis specification TAS
    Traceable Author Statement
    more info
    PubMed 
    dorsal/ventral pattern formation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    ectoderm development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    ectodermal cell fate specification TAS
    Traceable Author Statement
    more info
    PubMed 
    gastrulation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    gastrulation involving germ band extension TAS
    Traceable Author Statement
    more info
    PubMed 
    germ cell migration TAS
    Traceable Author Statement
    more info
    PubMed 
    heart development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    immune response IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    immune response NAS
    Non-traceable Author Statement
    more info
     
    immune response TAS
    Traceable Author Statement
    more info
    PubMed 
    maternal determination of anterior/posterior axis, embryo IMP
    Inferred from Mutant Phenotype
    more info
     
    melanization defense response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mesoderm development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    mesodermal cell fate specification TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of transcription, DNA-templated NAS
    Non-traceable Author Statement
    more info
    PubMed 
    negative regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    peripheral nervous system neuron development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    plasmatocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter TAS
    Traceable Author Statement
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of alternative mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of glucose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of hemocyte proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of transcription, DNA-templated NAS
    Non-traceable Author Statement
    more info
    PubMed 
    ventral cord development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm NAS
    Non-traceable Author Statement
    more info
     
    cytoplasm TAS
    Traceable Author Statement
    more info
    PubMed 
    neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IC
    Inferred by Curator
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus NAS
    Non-traceable Author Statement
    more info
    PubMed 
    nucleus TAS
    Traceable Author Statement
    more info
    PubMed 
    Preferred Names
    CG6667 gene product from transcript CG6667-RA
    Names
    CG6667-PA
    CG6667-PB
    CG6667-PC
    CG6667-PD
    CG6667-PE
    CG6667-PF
    NFkappabeta
    dl-PA
    dl-PB
    dl-PC
    dl-PD
    dl-PE
    dl-PF
    dorsal
    embryonic polarity protein dorsal

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      17436830..17450364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165217.3NP_724052.1  dorsal, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724052.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P15330
      UniProtKB/TrEMBL
      E1JHK3
      Related
      FBpp0080558, FBtr0081005
      Conserved Domains (2) summary
      cd07887
      Location:47220
      RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
      cd01177
      Location:225326
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    2. NM_165218.3NP_724053.1  dorsal, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724053.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P15330
      UniProtKB/TrEMBL
      E1JHK3
      Related
      FBpp0080559, FBtr0081006
      Conserved Domains (2) summary
      cd07887
      Location:47220
      RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
      cd01177
      Location:225326
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    3. NM_001169530.1NP_001163001.1  dorsal, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163001.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P15330
      UniProtKB/TrEMBL
      E1JHK3
      Related
      FBpp0290598, FBtr0301384
      Conserved Domains (2) summary
      cd07887
      Location:47220
      RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
      cd01177
      Location:225326
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    4. NM_001169529.1NP_001163000.1  dorsal, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163000.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P15330
      UniProtKB/TrEMBL
      E1JHK3
      Related
      FBpp0290597, FBtr0301383
      Conserved Domains (2) summary
      cd07887
      Location:47220
      RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
      cd01177
      Location:225326
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    5. NM_165219.2NP_724054.1  dorsal, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724054.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P15330
      UniProtKB/TrEMBL
      C7LA93
      Related
      FBpp0080560, FBtr0081007
      Conserved Domains (2) summary
      cd07887
      Location:47220
      RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
      cd01177
      Location:225326
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    6. NM_001299085.1NP_001286014.1  dorsal, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286014.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P15330
      UniProtKB/TrEMBL
      C7LA93
      Related
      FBpp0309222, FBtr0340250
      Conserved Domains (2) summary
      cd07887
      Location:47220
      RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
      cd01177
      Location:225326
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
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