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sod-1 Protein SOD-1 [ Caenorhabditis elegans ]

Gene ID: 174141, updated on 8-Feb-2015
Gene symbol
sod-1
Gene description
Protein SOD-1
Locus tag
CELE_C15F1.7
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (old-lineage: Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
See sod-1 in MapViewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.9 (6972834..6973838, complement)

Chromosome II - NC_003280.9Genomic Context describing neighboring genes Neighboring gene Protein ART-1 Neighboring gene ncRNA Neighboring gene Protein C15F1.8 Neighboring gene Protein C15F1.2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
antioxidant activity IEA
Inferred from Electronic Annotation
more info
 
copper ion binding IDA
Inferred from Direct Assay
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
superoxide dismutase activity IDA
Inferred from Direct Assay
more info
PubMed 
superoxide dismutase activity IEA
Inferred from Electronic Annotation
more info
 
superoxide dismutase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
age-dependent response to oxidative stress IDA
Inferred from Direct Assay
more info
PubMed 
determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
germ cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of vulval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
oviposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
oxidation-reduction process IDA
Inferred from Direct Assay
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
regulation of brood size IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of vulval development IGI
Inferred from Genetic Interaction
more info
PubMed 
removal of superoxide radicals IMP
Inferred from Mutant Phenotype
more info
PubMed 
striated muscle myosin thick filament assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
superoxide metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
superoxide metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IC
Inferred by Curator
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
Names
Protein SOD-1
NP_001021956.1
  • Confirmed by transcript evidence;~superoxide dismutase
NP_001021957.1
  • Confirmed by transcript evidence;~C. elegans SOD-1 protein; contains similarity to Pfam domain PF00080 Copper/zinc superoxide dismutase (SODC) contains similarity to Interpro domains IPR001424 (Superoxide dismutase, copper/zinc binding domain), IPR024134 (Superoxide dismutase (Cu/Zn) / chaperones), IPR018152 (Superoxide dismutase, copper/zinc, binding site)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.9 Reference assembly

    Range
    6972834..6973838
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026785.2NP_001021956.1  Protein SOD-1, isoform a [Caenorhabditis elegans]

    See proteins identical to NP_001021956.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34697
    Conserved Domains (1) summary
    cd00305
    Location:26171
    Cu-Zn_Superoxide_Dismutase; Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the ...
  2. NM_001026786.3NP_001021957.1  Protein SOD-1, isoform b [Caenorhabditis elegans]

    See proteins identical to NP_001021957.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34697
    Conserved Domains (1) summary
    cd00305
    Location:4149
    Cu-Zn_Superoxide_Dismutase; Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the ...