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    Tceb1 transcription elongation factor B subunit 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64525, updated on 23-Aug-2016
    Official Symbol
    Tceb1provided by RGD
    Official Full Name
    transcription elongation factor B subunit 1provided by RGD
    Primary source
    RGD:620658
    See related
    Ensembl:ENSRNOG00000031730
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Summary
    15 kDa subunit of the transcription factor B (SIII) complex, also known as elongin C; releases RNA polymerase II from transient pausing at arresting sites [RGD, Feb 2006]
    Orthologs
    Location:
    5q11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (2042991..2059357)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (2044009..2060375)

    Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene hypothetical LOC100361317 Neighboring gene transmembrane protein 70 Neighboring gene staufen double-stranded RNA binding protein 2 Neighboring gene non-histone chromosomal protein HMG-17-like Neighboring gene uncharacterized LOC102555040

    • ECS complex, organism-specific biosystem (from KEGG)
      ECS complex, organism-specific biosystemStructural complex; Genetic information processing; Ubiquitin system
    • ECS complex, conserved biosystem (from KEGG)
      ECS complex, conserved biosystemStructural complex; Genetic information processing; Ubiquitin system
    • ECV complex, organism-specific biosystem (from KEGG)
      ECV complex, organism-specific biosystemStructural complex; Genetic information processing; Ubiquitin system
    • ECV complex, conserved biosystem (from KEGG)
      ECV complex, conserved biosystemStructural complex; Genetic information processing; Ubiquitin system
    • HIF-1 signaling pathway, organism-specific biosystem (from KEGG)
      HIF-1 signaling pathway, organism-specific biosystemHypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. It consists of two subunits: an inducibly-expressed HIF-1alpha subunit and a c...
    • Pathways in cancer, organism-specific biosystem (from KEGG)
      Pathways in cancer, organism-specific biosystem
      Pathways in cancer
    • Renal cell carcinoma, organism-specific biosystem (from KEGG)
      Renal cell carcinoma, organism-specific biosystemRenal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal canc...
    • Renal cell carcinoma, conserved biosystem (from KEGG)
      Renal cell carcinoma, conserved biosystemRenal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal canc...
    • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
      Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
    • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
      Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC72822

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    protein complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    contributes_to ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to ubiquitin-protein transferase activity IC
    Inferred by Curator
    more info
    PubMed 
    Component Evidence Code Pubs
    VCB complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    elongin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    elongin complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    transcription elongation factor B polypeptide 1
    Names
    RNA polymerase II transcription factor SIII subunit C
    SIII p15
    eloC
    elongation factor SIII p15 subunit
    elongin 15 kDa subunit
    elongin-C
    stromal membrane-associated protein SMAP1B homolog
    transcription elongation factor B (SIII), polypeptide 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001270561.1NP_001257490.1  transcription elongation factor B polypeptide 1

      See identical proteins and their annotated locations for NP_001257490.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All four variants encode the same protein.
      Source sequence(s)
      AABR07046691, AI555412, FM110992
      UniProtKB/Swiss-Prot
      P83941
      Related
      ENSRNOP00000071456, ENSRNOT00000082813
      Conserved Domains (1) summary
      smart00512
      Location:16112
      Skp1; Found in Skp1 protein family
    2. NM_001270562.1NP_001257491.1  transcription elongation factor B polypeptide 1

      See identical proteins and their annotated locations for NP_001257491.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All four variants encode the same protein.
      Source sequence(s)
      AABR07046691, AI555412, FM110992
      UniProtKB/Swiss-Prot
      P83941
      Related
      ENSRNOP00000069739, ENSRNOT00000090313
      Conserved Domains (1) summary
      smart00512
      Location:16112
      Skp1; Found in Skp1 protein family
    3. NM_001270563.1NP_001257492.1  transcription elongation factor B polypeptide 1

      See identical proteins and their annotated locations for NP_001257492.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All four variants encode the same protein.
      Source sequence(s)
      AABR07046691, AI555412, FM101371, FM110992
      UniProtKB/Swiss-Prot
      P83941
      Conserved Domains (1) summary
      smart00512
      Location:16112
      Skp1; Found in Skp1 protein family
    4. NM_022593.4NP_072115.1  transcription elongation factor B polypeptide 1

      See identical proteins and their annotated locations for NP_072115.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All four variants encode the same protein.
      Source sequence(s)
      AABR07046691, AI555412, CK355540, FM093546
      UniProtKB/Swiss-Prot
      P83941
      Related
      ENSRNOP00000067410, ENSRNOT00000050236
      Conserved Domains (1) summary
      smart00512
      Location:16112
      Skp1; Found in Skp1 protein family

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

      Range
      2042991..2059357
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237724.3XP_006237786.1  

      See identical proteins and their annotated locations for XP_006237786.1

      UniProtKB/Swiss-Prot
      P83941
      Conserved Domains (1) summary
      smart00512
      Location:16112
      Skp1; Found in Skp1 protein family

    Alternate Rn_Celera

    Genomic

    1. AC_000073.1 Alternate Rn_Celera

      Range
      2283738..2300104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)