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LRRTM3 leucine rich repeat transmembrane neuronal 3 [ Homo sapiens (human) ]

Gene ID: 347731, updated on 11-Sep-2014
Official Symbol
LRRTM3provided by HGNC
Official Full Name
leucine rich repeat transmembrane neuronal 3provided by HGNC
Primary source
HGNC:HGNC:19410
Locus tag
UNQ803/PRO1693
See related
HPRD:14324; MIM:610869
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
See LRRTM3 in Epigenomics, MapViewer
Location:
10q21.3
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 10 NC_000010.11 (66926034..67101109)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (68685792..68861309)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene WW domain containing E3 ubiquitin protein ligase 2 pseudogene Neighboring gene long intergenic non-protein coding RNA 1515 Neighboring gene catenin (cadherin-associated protein), alpha 3 Neighboring gene uncharacterized LOC101928961 Neighboring gene ribosomal protein L7a pseudogene 51 Neighboring gene microRNA 7151

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Clone Names

  • MGC131810

Gene Ontology Provided by GOA

Process Evidence Code Pubs
positive regulation of beta-amyloid formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
leucine-rich repeat transmembrane neuronal protein 3
Names
leucine-rich repeat transmembrane neuronal protein 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178011.4NP_821079.3  leucine-rich repeat transmembrane neuronal protein 3 precursor

    See proteins identical to NP_821079.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the protein.
    Source sequence(s)
    AC022401, AC069536, BC111492
    Consensus CDS
    CCDS7270.1
    UniProtKB/Swiss-Prot
    Q86VH5
    Conserved Domains (3) summary
    smart00013
    Location:3361
    LRRNT; Leucine rich repeat N-terminal domain
    cd00116
    Location:81300
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam13855
    Location:133193
    LRR_8; Leucine rich repeat

RNA

  1. NR_111909.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two exons and contains two alternate 5' exons, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AC022401, BU154601, DB029785

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000010.11 

    Range
    66926034..67101109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
  2. NC_000010.11 

    Range
    67052063..67055018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_246122.1 RNA Sequence

Alternate HuRef

Genomic

  1. AC_000142.1 

    Range
    62684879..62859970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
  2. AC_000142.1 

    Range
    62810909..62813864
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_247527.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018921.2 

    Range
    68967601..69142679
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
  2. NC_018921.2 

    Range
    69093619..69096569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_252756.1 RNA Sequence