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    flavivirus polyprotein gene flavivirus polyprotein [ West Nile virus ]

    Gene ID: 5714902, updated on 23-Jan-2016
    Gene symbol
    flavivirus polyprotein gene
    Gene description
    flavivirus polyprotein
    Locus tag
    WNVNY99_gp1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    West Nile virus (strain: NY99, isolate: 385-99, gb-acronym: WNV)
    Lineage
    Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus; Japanese encephalitis virus group
    Sequence:
    NC_009942.1 (97..10398)

    NC_009942.1Genomic Context describing neighboring genes Neighboring gene Truncated version of polyprotein that will be produced when frameshifting occurs at nt 3552 Neighboring gene WARF4 open reading frame is only found in lineage 1 of West Nile virus. The existence of the protein has been shown indirectly

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Names
    flavivirus polyprotein
    capsid protein C
    anchored capsid protein C
    membrane glycoprotein precursor M
    envelope protein E
    nonstructural protein NS1
    nonstructural protein NS2A
    nonstructural protein NS2B
    nonstructural protein NS3
    nonstructural protein NS4A
    nonstructural protein NS4B
    RNA-dependent RNA polymerase NS5
    membrane glycoprotein M
    protein 2K
    protein pr

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_009942.1 Reference assembly

      Range
      97..10398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_001527877.1 flavivirus polyprotein [West Nile virus]

      See identical proteins and their annotated locations for YP_001527877.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q3HM13
      Conserved Domains (17) summary
      pfam01002
      Location:13781505
      Flavi_NS2B; Flavivirus non-structural protein NS2B
      pfam01570
      Location:128207
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam00948
      Location:7931147
      Flavi_NS1; Flavivirus non-structural Protein NS1
      pfam01350
      Location:21272271
      Flavi_NS4A; Flavivirus non-structural protein NS4A
      cd12149
      Location:598690
      Flavi_E_C; Immunoglobulin-like domain III (C-terminal domain) of Flavivirus envelope glycoprotein E
      TIGR04240
      Location:695791
      flavi_E_stem; flavivirus envelope glycoprotein E, stem/anchor domain
      smart00487
      Location:16861857
      DEXDc; DEAD-like helicases superfamily
      cd00046
      Location:16931824
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00869
      Location:291589
      Flavi_glycoprot; Flavivirus glycoprotein, central and dimerization domains
      pfam00949
      Location:15231673
      Peptidase_S7; Peptidase S7, Flavivirus NS3 serine protease
      pfam00972
      Location:27823424
      Flavi_NS5; Flavivirus RNA-directed RNA polymerase
      pfam01003
      Location:6123
      Flavi_capsid; Flavivirus capsid protein C
      pfam01004
      Location:218290
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01005
      Location:11551374
      Flavi_NS2A; Flavivirus non-structural protein NS2A
      pfam01349
      Location:22742522
      Flavi_NS4B; Flavivirus non-structural protein NS4B
      pfam01728
      Location:25832752
      FtsJ; FtsJ-like methyltransferase
      cl21455
      Location:18621970
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    2. YP_001527878.1 capsid protein C

      Conserved Domains (1) summary
      pfam01003
      Location:6105
      Flavi_capsid; Flavivirus capsid protein C
    3. YP_005097850.1 anchored capsid protein C

      Conserved Domains (1) summary
      pfam01003
      Location:6123
      Flavi_capsid; Flavivirus capsid protein C
    4. YP_001527879.1 membrane glycoprotein precursor M

      Conserved Domains (4) summary
      pfam01570
      Location:584
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam01004
      Location:95167
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:584
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam01004
      Location:95167
      Flavi_M; Flavivirus envelope glycoprotein M
    5. YP_001527880.1 envelope protein E

      Conserved Domains (3) summary
      cd12149
      Location:308400
      Flavi_E_C; Immunoglobulin-like domain III (C-terminal domain) of Flavivirus envelope glycoprotein E
      TIGR04240
      Location:405501
      flavi_E_stem; flavivirus envelope glycoprotein E, stem/anchor domain
      pfam00869
      Location:1299
      Flavi_glycoprot; Flavivirus glycoprotein, central and dimerization domains
    6. YP_001527881.1 nonstructural protein NS1

      Conserved Domains (1) summary
      pfam00948
      Location:2352
      Flavi_NS1; Flavivirus non-structural Protein NS1
    7. YP_001527882.1 nonstructural protein NS2A

      Conserved Domains (1) summary
      pfam01005
      Location:12231
      Flavi_NS2A; Flavivirus non-structural protein NS2A
    8. YP_001527883.1 nonstructural protein NS2B

      Conserved Domains (1) summary
      pfam01002
      Location:4131
      Flavi_NS2B; Flavivirus non-structural protein NS2B
    9. YP_001527884.1 nonstructural protein NS3

      Conserved Domains (4) summary
      smart00487
      Location:181352
      DEXDc; DEAD-like helicases superfamily
      cd00046
      Location:188319
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00949
      Location:18168
      Peptidase_S7; Peptidase S7, Flavivirus NS3 serine protease
      cl21455
      Location:357465
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    10. YP_001527885.1 nonstructural protein NS4A

      Conserved Domains (2) summary
      pfam01350
      Location:3147
      Flavi_NS4A; Flavivirus non-structural protein NS4A
      pfam01350
      Location:3147
      Flavi_NS4A; Flavivirus non-structural protein NS4A
    11. YP_001527886.1 nonstructural protein NS4B

      Conserved Domains (1) summary
      pfam01349
      Location:1249
      Flavi_NS4B; Flavivirus non-structural protein NS4B
    12. YP_001527887.1 RNA-dependent RNA polymerase NS5

      Conserved Domains (2) summary
      pfam00972
      Location:254896
      Flavi_NS5; Flavivirus RNA-directed RNA polymerase
      pfam01728
      Location:55224
      FtsJ; FtsJ-like methyltransferase
    13. YP_001527879.1 membrane glycoprotein M

      Conserved Domains (4) summary
      pfam01570
      Location:584
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam01004
      Location:95167
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:584
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam01004
      Location:95167
      Flavi_M; Flavivirus envelope glycoprotein M
    14. YP_001527885.1 protein 2K

      Conserved Domains (2) summary
      pfam01350
      Location:3147
      Flavi_NS4A; Flavivirus non-structural protein NS4A
      pfam01350
      Location:3147
      Flavi_NS4A; Flavivirus non-structural protein NS4A
    15. YP_009164953.1 protein pr

      Conserved Domains (1) summary
      pfam01570
      Location:591
      Flavi_propep; Flavivirus polyprotein propeptide