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    Kat6b K(lysine) acetyltransferase 6B [ Mus musculus (house mouse) ]

    Gene ID: 54169, updated on 24-Jun-2016
    Official Symbol
    Kat6bprovided by MGI
    Official Full Name
    K(lysine) acetyltransferase 6Bprovided by MGI
    Primary source
    MGI:MGI:1858746
    See related
    Ensembl:ENSMUSG00000021767 Vega:OTTMUSG00000043207
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    qkf; Morf; Myst4; MYST-4; AI507552; querkopf; mKIAA0383; B130044K16Rik
    Orthologs
    Location:
    14; 14 A3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (21498812..21672478)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (22319076..22491355)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene adenosine kinase Neighboring gene predicted gene, 41105 Neighboring gene predicted gene, 30363 Neighboring gene dual specificity phosphatase and pro isomerase domain containing 1 Neighboring gene dual specificity phosphatase 13

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1)  1 citation
    • Chemically induced (ENU) (1) 
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    histone acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    chromatin modification IEA
    Inferred from Electronic Annotation
    more info
     
    histone acetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleosome IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    histone acetyltransferase KAT6B
    Names
    MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4
    MYST histone acetyltransferase monocytic leukemia 4
    histone acetyltransferase MYST4
    histone acetyltransferase querkopf
    monocytic leukemia
    protein querkopf
    NP_001192170.1
    NP_059507.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205241.1NP_001192170.1  histone acetyltransferase KAT6B

      See identical proteins and their annotated locations for NP_001192170.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC148978, AK147509, BP753863
      Consensus CDS
      CCDS59615.1
      UniProtKB/TrEMBL
      Q3UH94
      Related
      ENSMUSP00000138511, OTTMUSP00000063397, ENSMUST00000182855, OTTMUST00000113317
      Conserved Domains (5) summary
      PLN03239
      Location:372698
      PLN03239; histone acetyltransferase; Provisional
      smart00526
      Location:94168
      H15; Domain in histone families 1 and 5
      pfam01853
      Location:482669
      MOZ_SAS; MOZ/SAS family
      cd15527
      Location:272318
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15689
      Location:213271
      PHD1_MORF; PHD finger 1 found in monocytic leukemia zinc finger protein-related factor (MORF)
    2. NM_017479.3NP_059507.2  histone acetyltransferase KAT6B

      See identical proteins and their annotated locations for NP_059507.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC115122, AC148978, AK052307, BC095974, BP753863
      Consensus CDS
      CCDS59615.1
      UniProtKB/Swiss-Prot
      Q8BRB7
      UniProtKB/TrEMBL
      Q501M5
      Related
      ENSMUSP00000138377, OTTMUSP00000063396, ENSMUST00000182405, OTTMUST00000113316
      Conserved Domains (5) summary
      PLN03239
      Location:372698
      PLN03239; histone acetyltransferase; Provisional
      smart00526
      Location:94168
      H15; Domain in histone families 1 and 5
      pfam01853
      Location:482669
      MOZ_SAS; MOZ/SAS family
      cd15527
      Location:272318
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15689
      Location:213271
      PHD1_MORF; PHD finger 1 found in monocytic leukemia zinc finger protein-related factor (MORF)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      21498812..21672478
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519265.3XP_006519328.1  

      See identical proteins and their annotated locations for XP_006519328.1

      Conserved Domains (5) summary
      PLN03239
      Location:662989
      PLN03239; histone acetyltransferase; Provisional
      smart00526
      Location:94168
      H15; Domain in histone families 1 and 5
      pfam01853
      Location:773960
      MOZ_SAS; MOZ/SAS family
      cd15527
      Location:272318
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15618
      Location:213270
      PHD1_MOZ_MORF; PHD finger 1 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
    2. XM_006519264.3XP_006519327.1  

      See identical proteins and their annotated locations for XP_006519327.1

      Conserved Domains (5) summary
      PLN03239
      Location:662989
      PLN03239; histone acetyltransferase; Provisional
      smart00526
      Location:94168
      H15; Domain in histone families 1 and 5
      pfam01853
      Location:773960
      MOZ_SAS; MOZ/SAS family
      cd15527
      Location:272318
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15618
      Location:213270
      PHD1_MOZ_MORF; PHD finger 1 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
    3. XM_017316082.1XP_017171571.1  

    4. XM_006519263.3XP_006519326.1  

      See identical proteins and their annotated locations for XP_006519326.1

      Conserved Domains (5) summary
      PLN03239
      Location:662989
      PLN03239; histone acetyltransferase; Provisional
      smart00526
      Location:94168
      H15; Domain in histone families 1 and 5
      pfam01853
      Location:773960
      MOZ_SAS; MOZ/SAS family
      cd15527
      Location:272318
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15618
      Location:213270
      PHD1_MOZ_MORF; PHD finger 1 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
    5. XM_006519268.3XP_006519331.1  

      See identical proteins and their annotated locations for XP_006519331.1

      UniProtKB/Swiss-Prot
      Q8BRB7
      Related
      ENSMUSP00000138421, OTTMUSP00000063398
      Conserved Domains (5) summary
      PLN03239
      Location:472807
      PLN03239; histone acetyltransferase; Provisional
      smart00526
      Location:94168
      H15; Domain in histone families 1 and 5
      pfam01853
      Location:591778
      MOZ_SAS; MOZ/SAS family
      cd15527
      Location:272318
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15689
      Location:213271
      PHD1_MORF; PHD finger 1 found in monocytic leukemia zinc finger protein-related factor (MORF)
    6. XM_017316083.1XP_017171572.1  

    7. XM_017316084.1XP_017171573.1  

    8. XM_006519269.3XP_006519332.1  

      Conserved Domains (3) summary
      PLN03239
      Location:377704
      PLN03239; histone acetyltransferase; Provisional
      pfam01853
      Location:488675
      MOZ_SAS; MOZ/SAS family
      cd15527
      Location:133
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
    9. XM_017316085.1XP_017171574.1