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Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase [ Rattus norvegicus (Norway rat) ]

Gene ID: 25275, updated on 6-Jul-2014
Official Symbol
Cnpprovided by RGD
Official Full Name
2',3'-cyclic nucleotide 3' phosphodiesteraseprovided by RGD
Primary source
RGD:2368
See related
Ensembl:ENSRNOG00000017496
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
CNPF; CNPI; Cnp1; CNPII
Summary
microtubule-binding protein that promotes microtubule assembly and may regulate cellular distribution of microtubules [RGD, Feb 2006]
See Cnp in MapViewer
Location:
10q32.1
Exon count :
6
Annotation release Status Assembly Chr Location
104 current Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (88284045..88290604)

Chromosome 10 - NC_005109.3Genomic Context describing neighboring genes Neighboring gene ATP citrate lyase Neighboring gene tetratricopeptide repeat domain 25 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 7 Neighboring gene NFKB inhibitor interacting Ras-like 2 Neighboring gene zinc finger protein 385C

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IDA
Inferred from Direct Assay
more info
PubMed 
2',3'-cyclic-nucleotide 3'-phosphodiesterase activity ISO
Inferred from Sequence Orthology
more info
 
2',3'-cyclic-nucleotide 3'-phosphodiesterase activity TAS
Traceable Author Statement
more info
PubMed 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
cyclic nucleotide binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
adult locomotory behavior IEA
Inferred from Electronic Annotation
more info
 
adult locomotory behavior ISO
Inferred from Sequence Orthology
more info
 
aging IEP
Inferred from Expression Pattern
more info
 
axonogenesis IEA
Inferred from Electronic Annotation
more info
 
axonogenesis ISO
Inferred from Sequence Orthology
more info
 
cyclic nucleotide catabolic process IEA
Inferred from Electronic Annotation
more info
 
forebrain development IEP
Inferred from Expression Pattern
more info
PubMed 
microtubule cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
oligodendrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of mitochondrial membrane permeability IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to lipopolysaccharide IEP
Inferred from Expression Pattern
more info
PubMed 
response to toxic substance IEA
Inferred from Electronic Annotation
more info
 
response to toxic substance ISO
Inferred from Sequence Orthology
more info
 
substantia nigra development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell projection IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular space IEA
Inferred from Electronic Annotation
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
melanosome IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
microtubule ISO
Inferred from Sequence Orthology
more info
 
microvillus IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
myelin sheath abaxonal region IDA
Inferred from Direct Assay
more info
PubMed 
myelin sheath adaxonal region IDA
Inferred from Direct Assay
more info
PubMed 
NOT nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
pseudopodium IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Names
2',3'-cyclic-nucleotide 3'-phosphodiesterase
CNPase
NP_036941.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012809.2NP_036941.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase

    See proteins identical to NP_036941.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098066
    UniProtKB/Swiss-Prot
    P13233
    Related
    ENSRNOP00000023875, ENSRNOT00000023872
    Conserved Domains (3) summary
    pfam05881
    Location:185399
    Blast Score: 918
    CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
    pfam13671
    Location:52165
    Blast Score: 154
    AAA_33; AAA domain
    cl19128
    Location:51176
    Blast Score: 113
    AAA_17; AAA domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_5.0 Primary Assembly

Genomic

  1. NC_005109.3 

    Range
    88284045..88290604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006247261.1XP_006247323.1  

    See proteins identical to XP_006247323.1

    Conserved Domains (3) summary
    pfam05881
    Location:165379
    Blast Score: 918
    CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
    pfam13671
    Location:32145
    Blast Score: 154
    AAA_33; AAA domain
    cl19128
    Location:31156
    Blast Score: 112
    AAA_17; AAA domain
  2. XM_006247260.1XP_006247322.1  

    See proteins identical to XP_006247322.1

    Conserved Domains (3) summary
    pfam05881
    Location:165379
    Blast Score: 918
    CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
    pfam13671
    Location:32145
    Blast Score: 154
    AAA_33; AAA domain
    cl19128
    Location:31156
    Blast Score: 112
    AAA_17; AAA domain

Alternate Rn_Celera

Genomic

  1. AC_000078.1 

    Range
    84227529..84234088
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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