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MYO6 myosin VI [ Sus scrofa (pig) ]

Gene ID: 397085, updated on 5-May-2015
Gene symbol
MYO6
Gene description
myosin VI
See related
Ensembl:ENSSSCG00000004478
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
Orthologs
See MYO6 in MapViewer
Location:
chromosome: 1
Exon count:
37
Annotation release Status Assembly Chr Location
104 current Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (100972528..101143893, complement)

Chromosome 1 - NC_010443.4Genomic Context describing neighboring genes Neighboring gene adenosylhomocysteinase pseudogene Neighboring gene interphotoreceptor matrix proteoglycan 1-like Neighboring gene interphotoreceptor matrix proteoglycan 1-like Neighboring gene sentrin-specific protease 6-like Neighboring gene SUMO1/sentrin specific peptidase 6

Genomic Sequence:
NC_010443.4 chromosome 1 reference Sscrofa10.2 Primary Assembly

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by GO

Function Evidence Code Pubs
ADP binding IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
actin filament binding IC
Inferred by Curator
more info
PubMed 
actin filament binding IDA
Inferred from Direct Assay
more info
PubMed 
calmodulin binding IPI
Inferred from Physical Interaction
more info
PubMed 
calmodulin binding NAS
Non-traceable Author Statement
more info
PubMed 
motor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
DNA damage response, signal transduction by p53 class mediator ISS
Inferred from Sequence or Structural Similarity
more info
 
actin filament-based movement IDA
Inferred from Direct Assay
more info
PubMed 
endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription from RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
sensory perception of sound IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
DNA-directed RNA polymerase II, holoenzyme ISS
Inferred from Sequence or Structural Similarity
more info
 
Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with clathrin-coated endocytic vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
NOT coated pit IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic membrane-bounded vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
colocalizes_with endocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
filamentous actin IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with filamentous actin IMP
Inferred from Mutant Phenotype
more info
PubMed 
myosin complex IEA
Inferred from Electronic Annotation
more info
 
nuclear membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
ruffle ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
unconventional myosin-VI
Names
unconventional myosin-VI
myosin-VI
unconventional myosin
unconventional myosin-6

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214021.1NP_999186.1  unconventional myosin-VI

    See identical proteins and their annotated locations for NP_999186.1

    Status: PROVISIONAL

    Source sequence(s)
    Z35331
    UniProtKB/Swiss-Prot
    Q29122
    Conserved Domains (1) summary
    cd01382
    Location:54772
    MYSc_type_VI; Myosin motor domain, type VI myosins. Myosin VI is a monomeric myosin, which moves towards the minus-end of actin filaments, in contrast to most other myosins. It has been implicated in endocytosis, secretion, and cell migration. This catalytic (head) ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa10.2 Primary Assembly

Genomic

  1. NC_010443.4 Reference Sscrofa10.2 Primary Assembly

    Range
    100972528..101143893
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005659429.1XP_005659486.1  

    See identical proteins and their annotated locations for XP_005659486.1

    UniProtKB/TrEMBL
    F1RQI7
    Related
    ENSSSCP00000004831, ENSSSCT00000004948
    Conserved Domains (1) summary
    cd01382
    Location:54771
    MYSc_type_VI; Myosin motor domain, type VI myosins. Myosin VI is a monomeric myosin, which moves towards the minus-end of actin filaments, in contrast to most other myosins. It has been implicated in endocytosis, secretion, and cell migration. This catalytic (head) ...
  2. XM_005659428.1XP_005659485.1  

    Conserved Domains (1) summary
    cd01382
    Location:54771
    MYSc_type_VI; Myosin motor domain, type VI myosins. Myosin VI is a monomeric myosin, which moves towards the minus-end of actin filaments, in contrast to most other myosins. It has been implicated in endocytosis, secretion, and cell migration. This catalytic (head) ...
  3. XM_005659427.1XP_005659484.1  

    Conserved Domains (2) summary
    COG4942
    Location:8451074
    COG4942; Membrane-bound metallopeptidase [Cell division and chromosome partitioning]
    cd01382
    Location:54771
    MYSc_type_VI; Myosin motor domain, type VI myosins. Myosin VI is a monomeric myosin, which moves towards the minus-end of actin filaments, in contrast to most other myosins. It has been implicated in endocytosis, secretion, and cell migration. This catalytic (head) ...
  4. XM_005659431.1XP_005659488.1  

    Conserved Domains (1) summary
    cd01382
    Location:54771
    MYSc_type_VI; Myosin motor domain, type VI myosins. Myosin VI is a monomeric myosin, which moves towards the minus-end of actin filaments, in contrast to most other myosins. It has been implicated in endocytosis, secretion, and cell migration. This catalytic (head) ...
  5. XM_005659426.1XP_005659483.1  

    Conserved Domains (1) summary
    cd01382
    Location:54771
    MYSc_type_VI; Myosin motor domain, type VI myosins. Myosin VI is a monomeric myosin, which moves towards the minus-end of actin filaments, in contrast to most other myosins. It has been implicated in endocytosis, secretion, and cell migration. This catalytic (head) ...
  6. XM_005659430.1XP_005659487.1  

    See identical proteins and their annotated locations for XP_005659487.1

    UniProtKB/TrEMBL
    F1RQI7
    Conserved Domains (1) summary
    cd01382
    Location:54771
    MYSc_type_VI; Myosin motor domain, type VI myosins. Myosin VI is a monomeric myosin, which moves towards the minus-end of actin filaments, in contrast to most other myosins. It has been implicated in endocytosis, secretion, and cell migration. This catalytic (head) ...