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DRC7 dynein regulatory complex subunit 7 [ Homo sapiens (human) ]

Gene ID: 84229, updated on 12-Apr-2015
Official Symbol
DRC7provided by HGNC
Official Full Name
dynein regulatory complex subunit 7provided by HGNC
Primary source
HGNC:HGNC:25289
See related
Ensembl:ENSG00000159625; HPRD:10902; Vega:OTTHUMG00000133473
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAP50; CFAP50; CCDC135; C16orf50
Orthologs
See DRC7 in MapViewer
Location:
16q21
Exon count:
19
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 16 NC_000016.10 (57694801..57731455)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (57728713..57765367)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor G1 Neighboring gene uncharacterized LOC105371292 Neighboring gene adhesion G protein-coupled receptor G3 Neighboring gene mitochondrial carrier 2 pseudogene Neighboring gene katanin p80 (WD repeat containing) subunit B 1 Neighboring gene kinesin family member C3 Neighboring gene microRNA 6772

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp434I099

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
motile cilium IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
dynein regulatory complex subunit 7
Names
dynein regulatory complex subunit 7
coiled-coil domain containing 135
coiled-coil domain-containing protein 135
coiled-coil domain-containing protein lobo homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289162.1NP_001276091.1  dynein regulatory complex subunit 7 isoform a

    See identical proteins and their annotated locations for NP_001276091.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AK093035, AK292558, BC030661, BC036667, DB093780
    Consensus CDS
    CCDS10787.1
    UniProtKB/Swiss-Prot
    Q8IY82
    Related
    ENSP00000353942, OTTHUMP00000254872, ENST00000360716, OTTHUMT00000433323
    Conserved Domains (1) summary
    pfam01841
    Location:173210
    Transglut_core; Transglutaminase-like superfamily
  2. NM_001289163.1NP_001276092.1  dynein regulatory complex subunit 7 isoform b

    See identical proteins and their annotated locations for NP_001276092.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a.
    Source sequence(s)
    AK093035, BC036667, DB093780
    Consensus CDS
    CCDS73894.1
    UniProtKB/Swiss-Prot
    Q8IY82
    Related
    ENSP00000338938, OTTHUMP00000255102, ENST00000336825, OTTHUMT00000433776
  3. NM_032269.5NP_115645.4  dynein regulatory complex subunit 7 isoform a

    See identical proteins and their annotated locations for NP_115645.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AK292558, BC036667, DB095284
    Consensus CDS
    CCDS10787.1
    UniProtKB/Swiss-Prot
    Q8IY82
    Related
    ENSP00000377869, OTTHUMP00000164678, ENST00000394337, OTTHUMT00000257349
    Conserved Domains (1) summary
    pfam01841
    Location:173210
    Transglut_core; Transglutaminase-like superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p2 Primary Assembly

    Range
    57694801..57731455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011523377.1XP_011521679.1  

    Conserved Domains (1) summary
    pfam01841
    Location:173210
    Transglut_core; Transglutaminase-like superfamily
  2. XM_011523378.1XP_011521680.1  

    See identical proteins and their annotated locations for XP_011521680.1

Alternate CHM1_1.1

Genomic

  1. NC_018927.2 Alternate CHM1_1.1

    Range
    59134320..59172147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)