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TTC12 tetratricopeptide repeat domain 12 [ Homo sapiens (human) ]

Gene ID: 54970, updated on 26-Nov-2014
Official Symbol
TTC12provided by HGNC
Official Full Name
tetratricopeptide repeat domain 12provided by HGNC
Primary source
HGNC:HGNC:23700
Locus tag
RP11-159N11.4
See related
Ensembl:ENSG00000149292; HPRD:15577; MIM:610732; Vega:OTTHUMG00000142832
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TPARM
See TTC12 in Epigenomics, MapViewer
Location:
11q23.2
Exon count:
26
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 11 NC_000011.10 (113314529..113373297)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (113185251..113244345)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928847 Neighboring gene neural cell adhesion molecule 1 Neighboring gene NCAM1 antisense RNA1 Neighboring gene ankyrin repeat and kinase domain containing 1 Neighboring gene dopamine receptor D2 Neighboring gene microRNA 4301

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ13859, FLJ20535
Preferred Names
tetratricopeptide repeat protein 12
Names
tetratricopeptide repeat protein 12
TPR repeat protein 12
tetratricopeptide repeat protein 12 variant 1
tetratricopeptide repeat protein 12 variant 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017868.3NP_060338.3  tetratricopeptide repeat protein 12

    See proteins identical to NP_060338.3

    Status: VALIDATED

    Source sequence(s)
    AK023921, AK223117, DB110945
    Consensus CDS
    CCDS8360.2
    UniProtKB/TrEMBL
    A8K8G6
    UniProtKB/TrEMBL
    Q53G14
    UniProtKB/Swiss-Prot
    Q9H892
    Related
    ENSP00000433757, OTTHUMP00000183510, ENST00000529221, OTTHUMT00000286455
    Conserved Domains (3) summary
    cd00020
    Location:526631
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00189
    Location:107206
    TPR; Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
    pfam13414
    Location:106171
    TPR_11; TPR repeat

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000011.10 

    Range
    113314529..113373297
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005271607.1XP_005271664.1  

    See proteins identical to XP_005271664.1

    UniProtKB/TrEMBL
    B0YJB4
    Related
    ENSP00000435291, OTTHUMP00000233106, ENST00000494714, OTTHUMT00000286458
    Conserved Domains (3) summary
    cd00020
    Location:526631
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00189
    Location:107206
    TPR; Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
    pfam13414
    Location:106171
    TPR_11; TPR repeat
  2. XM_005271603.2XP_005271660.1  

    See proteins identical to XP_005271660.1

    Conserved Domains (3) summary
    cd00020
    Location:526631
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00189
    Location:107206
    TPR; Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
    pfam13414
    Location:106171
    TPR_11; TPR repeat
  3. XM_005271606.2XP_005271663.1  

    Conserved Domains (3) summary
    cd00020
    Location:526631
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00189
    Location:107206
    TPR; Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
    pfam13414
    Location:106171
    TPR_11; TPR repeat
  4. XM_006718866.1XP_006718929.1  

    Conserved Domains (3) summary
    cd00020
    Location:526631
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00189
    Location:107206
    TPR; Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
    pfam13414
    Location:106171
    TPR_11; TPR repeat
  5. XM_005271605.2XP_005271662.1  

    See proteins identical to XP_005271662.1

    Conserved Domains (3) summary
    cd00020
    Location:526631
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00189
    Location:107206
    TPR; Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
    pfam13414
    Location:106171
    TPR_11; TPR repeat
  6. XM_005271604.2XP_005271661.1  

    See proteins identical to XP_005271661.1

    Conserved Domains (3) summary
    cd00020
    Location:526631
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00189
    Location:107206
    TPR; Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
    pfam13414
    Location:106171
    TPR_11; TPR repeat

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 

    Range
    113068217..113120081
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000143.1 

    Range
    109112836..109164715
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)