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    Ppp1r9a protein phosphatase 1, regulatory (inhibitor) subunit 9A [ Mus musculus (house mouse) ]

    Gene ID: 243725, updated on 26-Jun-2016
    Official Symbol
    Ppp1r9aprovided by MGI
    Official Full Name
    protein phosphatase 1, regulatory (inhibitor) subunit 9Aprovided by MGI
    Primary source
    MGI:MGI:2442401
    See related
    Ensembl:ENSMUSG00000032827 Vega:OTTMUSG00000042256
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NRB; BB181831; mKIAA1222; 5330407E15; neurabin-I; 2810430P21Rik; 4930518N04Rik; A230094E16Rik
    Orthologs
    Location:
    6 A1; 6 1.86 cM
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (4902744..5165661)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (4853320..5115661)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene predicted gene 20714 Neighboring gene predicted pseudogene 9835 Neighboring gene uncharacterized LOC108169128 Neighboring gene paraoxonase 1 Neighboring gene paraoxonase 3

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    ion channel binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase 1 binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    actin filament organization IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    calcium-mediated signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to toxic substance ISO
    Inferred from Sequence Orthology
    more info
     
    excitatory postsynaptic potential ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of long-term synaptic potentiation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of spontaneous neurotransmitter secretion ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of stress fiber assembly ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neuron projection development ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of dendritic spine development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of long term synaptic depression ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of actin filament polymerization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of filopodium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of synapse assembly ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of synapse structural plasticity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    cortical actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic spine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic spine neck ISO
    Inferred from Sequence Orthology
    more info
     
    filopodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    filopodium ISO
    Inferred from Sequence Orthology
    more info
     
    growth cone ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    growth cone lamellipodium ISO
    Inferred from Sequence Orthology
    more info
     
    lamellipodium ISO
    Inferred from Sequence Orthology
    more info
     
    neuromuscular junction ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    synapse ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    neurabin-1
    Names
    Neurabin I
    neural tissue-specific F-actin binding protein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181595.3NP_853626.1  neurabin-1

      See identical proteins and their annotated locations for NP_853626.1

      Status: PROVISIONAL

      Source sequence(s)
      AC068500, AC074225
      Consensus CDS
      CCDS19897.1
      UniProtKB/TrEMBL
      Q7TN74
      Related
      ENSMUSP00000046906, OTTMUSP00000062093, ENSMUST00000035813, OTTMUST00000111089
      Conserved Domains (5) summary
      pfam07106
      Location:663773
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:9831052
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:9861050
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15327
      Location:876948
      Tankyrase_bdg_C; Tankyrase binding protein C terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      4902744..5165661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505071.3XP_006505134.1  

      See identical proteins and their annotated locations for XP_006505134.1

      Conserved Domains (4) summary
      pfam07106
      Location:685795
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:12101279
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:12131277
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    2. XM_006505079.3XP_006505142.1  

      See identical proteins and their annotated locations for XP_006505142.1

      UniProtKB/TrEMBL
      Q7TN74
      Related
      ENSMUSP00000135629, OTTMUSP00000062092, ENSMUST00000175889, OTTMUST00000111088
      Conserved Domains (5) summary
      pfam07106
      Location:663773
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:9831052
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:9861050
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15327
      Location:876948
      Tankyrase_bdg_C; Tankyrase binding protein C terminal domain
    3. XM_006505070.2XP_006505133.1  

      See identical proteins and their annotated locations for XP_006505133.1

      Conserved Domains (4) summary
      pfam07106
      Location:685795
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:12101279
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:12131277
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    4. XM_006505073.2XP_006505136.1  

      See identical proteins and their annotated locations for XP_006505136.1

      Conserved Domains (4) summary
      pfam07106
      Location:685795
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:12021271
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:12051269
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    5. XM_017321590.1XP_017177079.1  

    6. XM_006505075.2XP_006505138.1  

      Conserved Domains (4) summary
      pfam07106
      Location:663773
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:11881257
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:11911255
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    7. XM_006505076.2XP_006505139.1  

      UniProtKB/TrEMBL
      H3BJD6
      Related
      ENSMUSP00000134943, OTTMUSP00000062112, ENSMUST00000177456, OTTMUST00000111117
      Conserved Domains (4) summary
      pfam07106
      Location:663773
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:11801249
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:11831247
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    8. XM_006505082.2XP_006505145.1  

      Related
      ENSMUSP00000134937, OTTMUSP00000062097, ENSMUST00000176263, OTTMUST00000111093
      Conserved Domains (2) summary
      pfam07106
      Location:685795
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    9. XM_011241059.1XP_011239361.1  

      Conserved Domains (2) summary
      pfam07106
      Location:685795
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    10. XM_006505078.2XP_006505141.1  

      Conserved Domains (5) summary
      pfam07106
      Location:685795
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:10051074
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:10081072
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15327
      Location:898970
      Tankyrase_bdg_C; Tankyrase binding protein C terminal domain
    11. XM_006505080.2XP_006505143.1  

      Conserved Domains (5) summary
      pfam07106
      Location:663773
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:9751044
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:9781042
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15327
      Location:876948
      Tankyrase_bdg_C; Tankyrase binding protein C terminal domain
    12. XM_017321591.1XP_017177080.1  

      Related
      ENSMUSP00000135485, OTTMUSP00000062111, ENSMUST00000177153, OTTMUST00000111116
    13. XM_006505072.3XP_006505135.1  

      See identical proteins and their annotated locations for XP_006505135.1

      Conserved Domains (4) summary
      pfam07106
      Location:685795
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cd09512
      Location:12101279
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:12131277
      SAM; Sterile alpha motif
      cd00992
      Location:506589
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...