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    Nt5e 5' nucleotidase, ecto [ Mus musculus (house mouse) ]

    Gene ID: 23959, updated on 9-Aug-2016
    Official Symbol
    Nt5eprovided by MGI
    Official Full Name
    5' nucleotidase, ectoprovided by MGI
    Primary source
    MGI:MGI:99782
    See related
    Ensembl:ENSMUSG00000032420 Vega:OTTMUSG00000045593
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NT; Nt5; eNT; CD73; AI447961; 2210401F01Rik
    Orthologs
    Location:
    9; 9 E3.2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (88327609..88372089)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (88222447..88266927)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene 28231 Neighboring gene solute carrier family 25, member 40 pseudogene Neighboring gene sorting nexin 14 Neighboring gene 60S ribosomal protein L21 pseudogene Neighboring gene synaptotagmin binding, cytoplasmic RNA interacting protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    5'-nucleotidase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    5'-nucleotidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    ferrous iron binding ISO
    Inferred from Sequence Orthology
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    AMP catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    AMP catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    adenosine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    adenosine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    leukocyte cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of inflammatory response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleotide catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    purine nucleotide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    anchored component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    synaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    5'-nucleotidase
    Names
    5'-NT
    ecto-5'-nucleotidase
    NP_035981.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011851.4NP_035981.1  5'-nucleotidase precursor

      See identical proteins and their annotated locations for NP_035981.1

      Status: VALIDATED

      Source sequence(s)
      AK029979, BB850214
      Consensus CDS
      CCDS23386.1
      UniProtKB/Swiss-Prot
      Q61503
      UniProtKB/TrEMBL
      Q0VEE0
      Related
      ENSMUSP00000034992, OTTMUSP00000066453, ENSMUST00000034992, OTTMUST00000119469
      Conserved Domains (3) summary
      COG0737
      Location:21534
      UshA; 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family [Nucleotide transport and metabolism, Defense mechanisms]
      cd07409
      Location:31312
      MPP_CD73_N; CD73 ecto-5'-nucleotidase and related proteins, N-terminal metallophosphatase domain
      pfam02872
      Location:354509
      5_nucleotid_C; 5'-nucleotidase, C-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      88327609..88372089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)