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Xcl1 chemokine (C motif) ligand 1 [ Mus musculus (house mouse) ]

Gene ID: 16963, updated on 19-Sep-2014
Official Symbol
Xcl1provided by MGI
Official Full Name
chemokine (C motif) ligand 1provided by MGI
Primary source
MGI:MGI:104593
See related
Ensembl:ENSMUSG00000026573; Vega:OTTMUSG00000026875
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LTN; ATAC; Lptn; SCM-1; Scyc1; SCM-1a; AI661682
See Xcl1 in Epigenomics, MapViewer
Location:
1 H2.2; 1 72.26 cM
Exon count:
3
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 1 NC_000067.6 (164931648..164935510, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102635160 Neighboring gene dermatopontin Neighboring gene uncharacterized LOC102635269 Neighboring gene predicted gene, 20743 Neighboring gene RIKEN cDNA 1700029M03 gene Neighboring gene uncharacterized LOC102635565

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
chemokine activity IDA
Inferred from Direct Assay
more info
PubMed 
chemokine activity ISO
Inferred from Sequence Orthology
more info
 
chemokine receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
chemokine receptor binding ISO
Inferred from Sequence Orthology
more info
 
chemokine receptor binding NAS
Non-traceable Author Statement
more info
 
cytokine activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell-cell signaling ISO
Inferred from Sequence Orthology
more info
 
cellular response to interleukin-4 IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to transforming growth factor beta stimulus IDA
Inferred from Direct Assay
more info
PubMed 
chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
immune response IEA
Inferred from Electronic Annotation
more info
 
mature natural killer cell chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
mature natural killer cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of CD4-positive, alpha-beta T cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of T cell cytokine production ISO
Inferred from Sequence Orthology
more info
 
negative regulation of T-helper 1 cell activation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of interferon-gamma production ISO
Inferred from Sequence Orthology
more info
 
negative regulation of interleukin-2 production ISO
Inferred from Sequence Orthology
more info
 
negative regulation of sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
positive regulation of B cell chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of CD4-positive, alpha-beta T cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of CD8-positive, alpha-beta T cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of T cell chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of T cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of T cell cytokine production IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of T cell mediated cytotoxicity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of T-helper 1 cell cytokine production IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of T-helper 2 cell cytokine production IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of granzyme A production ISO
Inferred from Sequence Orthology
more info
 
positive regulation of granzyme B production ISO
Inferred from Sequence Orthology
more info
 
positive regulation of immune response to tumor cell NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of immunoglobulin production in mucosal tissue IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of innate immune response IC
Inferred by Curator
more info
PubMed 
positive regulation of interleukin-10 production ISO
Inferred from Sequence Orthology
more info
 
positive regulation of leukocyte chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of natural killer cell chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of natural killer cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neutrophil chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
 
positive regulation of thymocyte migration IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transforming growth factor beta production ISO
Inferred from Sequence Orthology
more info
 
regulation of inflammatory response IC
Inferred by Curator
more info
PubMed 
regulation of inflammatory response ISO
Inferred from Sequence Orthology
more info
 
release of sequestered calcium ion into cytosol IDA
Inferred from Direct Assay
more info
PubMed 
response to virus ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
lymphotactin
Names
lymphotactin
lymphotaxin
cytokine SCM-1
c motif chemokine 1
small-inducible cytokine C1
small inducible cytokine subfamily C, member 1 (lymphotactin)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008510.1NP_032536.1  lymphotactin precursor

    See proteins identical to NP_032536.1

    Status: PROVISIONAL

    Source sequence(s)
    D43769
    Consensus CDS
    CCDS15438.1
    UniProtKB/Swiss-Prot
    P47993
    UniProtKB/TrEMBL
    Q542T1
    Related
    ENSMUSP00000027860, OTTMUSP00000033314, ENSMUST00000027860, OTTMUST00000066472
    Conserved Domains (1) summary
    cd00271
    Location:2293
    Chemokine_C; Chemokine_C, C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000067.6 

    Range
    164931648..164935510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 

    Range
    167368241..167372103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)