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Ganab alpha glucosidase 2 alpha neutral subunit [ Mus musculus (house mouse) ]

Gene ID: 14376, updated on 19-Sep-2014
Official Symbol
Ganabprovided by MGI
Official Full Name
alpha glucosidase 2 alpha neutral subunitprovided by MGI
Primary source
MGI:MGI:1097667
See related
Ensembl:ENSMUSG00000071650
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G2an; GluII; AU042638; mKIAA0088
See Ganab in Epigenomics, MapViewer
Location:
19 A; 19
Exon count:
26
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 19 NC_000085.6 (8898051..8916734)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102308570 Neighboring gene RIKEN cDNA 1810009A15 gene Neighboring gene integrator complex subunit 5 Neighboring gene uncharacterized LOC102640604 Neighboring gene beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) Neighboring gene rod outer segment membrane protein 1

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC144011, MGC144012

Gene Ontology Provided by MGI

Function Evidence Code Pubs
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
glucan 1,3-alpha-glucosidase activity IEA
Inferred from Electronic Annotation
more info
 
glucosidase activity ISA
Inferred from Sequence Alignment
more info
PubMed 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
N-glycan processing TAS
Traceable Author Statement
more info
PubMed 
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum TAS
Traceable Author Statement
more info
PubMed 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
glucosidase II complex IPI
Inferred from Physical Interaction
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
neutral alpha-glucosidase AB
Names
neutral alpha-glucosidase AB
alpha-glucosidase 2
glucosidase II alpha-subunit
glucosidase II subunit alpha
carbohydrate processing enzyme of the endoplasmic reticulum
NP_032086.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293621.1NP_001280550.1  neutral alpha-glucosidase AB isoform 2 precursor

    See proteins identical to NP_001280550.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. The encoded protein (isoform 2) is shorter, compared to isoform 1.
    Source sequence(s)
    AC129217, AK081915, BB002622, BC094437
    Conserved Domains (3) summary
    cd06603
    Location:384722
    GH31_GANC_GANAB_alpha; This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in ...
    pfam01055
    Location:365810
    Glyco_hydro_31; Glycosyl hydrolases family 31
    pfam13802
    Location:254324
    Gal_mutarotas_2; Galactose mutarotase-like
  2. NM_008060.2NP_032086.1  neutral alpha-glucosidase AB isoform 1

    See proteins identical to NP_032086.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC129217, AK030722, AK081915, BB002622, BC128069
    Consensus CDS
    CCDS29557.1
    UniProtKB/TrEMBL
    A1A4T2
    UniProtKB/Swiss-Prot
    Q8BHN3
    Related
    ENSMUSP00000093965, ENSMUST00000096246
    Conserved Domains (3) summary
    cd06603
    Location:406744
    GH31_GANC_GANAB_alpha; This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in ...
    pfam01055
    Location:387832
    Glyco_hydro_31; Glycosyl hydrolases family 31
    pfam13802
    Location:276346
    Gal_mutarotas_2; Galactose mutarotase-like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000085.6 

    Range
    8898051..8916734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526676.1XP_006526739.1  

    Conserved Domains (3) summary
    cd06603
    Location:384722
    GH31_GANC_GANAB_alpha; This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in ...
    pfam01055
    Location:365810
    Glyco_hydro_31; Glycosyl hydrolases family 31
    pfam13802
    Location:254324
    Gal_mutarotas_2; Galactose mutarotase-like
  2. XM_006526677.1XP_006526740.1  

    Conserved Domains (3) summary
    cd06603
    Location:309647
    GH31_GANC_GANAB_alpha; This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in ...
    pfam01055
    Location:290735
    Glyco_hydro_31; Glycosyl hydrolases family 31
    pfam13802
    Location:179249
    Gal_mutarotas_2; Galactose mutarotase-like
  3. XM_006526678.1XP_006526741.1  

    Conserved Domains (3) summary
    cd06603
    Location:287625
    GH31_GANC_GANAB_alpha; This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in ...
    pfam01055
    Location:268713
    Glyco_hydro_31; Glycosyl hydrolases family 31
    pfam13802
    Location:157227
    Gal_mutarotas_2; Galactose mutarotase-like

Alternate Mm_Celera

Genomic

  1. AC_000041.1 

    Range
    8658850..8677438
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)