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Nsfl1c NSFL1 (p97) cofactor (p47) [ Mus musculus (house mouse) ]

Gene ID: 386649, updated on 19-Jul-2014
Official Symbol
Nsfl1cprovided by MGI
Official Full Name
NSFL1 (p97) cofactor (p47)provided by MGI
Primary source
MGI:3042273
Locus tag
RP23-419G21.4
See related
Ensembl:ENSMUSG00000027455; Vega:OTTMUSG00000015798
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p47; Stxbp3a; Munc-18c
See Nsfl1c in Epigenomics, MapViewer
Location:
2 G3; 2
Exon count :
10
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 2 NC_000068.7 (151494187..151511308)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4921509C19 gene Neighboring gene tubulin, alpha 1C pseudogene Neighboring gene uncharacterized LOC102633071 Neighboring gene FK506 binding protein 1a

  • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
  • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATPase binding ISO
Inferred from Sequence Orthology
more info
 
lipid binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to phospholipid binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ubiquitin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
Golgi organization ISO
Inferred from Sequence Orthology
more info
 
membrane fusion ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
chromosome IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
intermediate filament cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
NSFL1 cofactor p47
Names
NSFL1 cofactor p47
p97 cofactor p47

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291074.1NP_001278003.1  NSFL1 cofactor p47 isoform b

    See proteins identical to NP_001278003.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
    Source sequence(s)
    AK013024, AL928719, CJ152490
    Consensus CDS
    CCDS71160.1
    UniProtKB/Swiss-Prot
    Q9CZ44
    Conserved Domains (3) summary
    cd01770
    Location:292370
    Blast Score: 391
    p47_UBX; p47-like ubiquitin domain
    smart00553
    Location:178270
    Blast Score: 409
    SEP; Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47
    pfam14555
    Location:648
    Blast Score: 161
    UBA_4; UBA-like domain
  2. NM_198326.3NP_938085.1  NSFL1 cofactor p47 isoform a

    See proteins identical to NP_938085.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK137088, AL928719, CJ152490
    Consensus CDS
    CCDS16868.1
    UniProtKB/TrEMBL
    Q3UVN5
    UniProtKB/Swiss-Prot
    Q9CZ44
    Related
    ENSMUSP00000086542, OTTMUSP00000016841, ENSMUST00000089140, OTTMUST00000037573
    Conserved Domains (3) summary
    cd01770
    Location:294372
    Blast Score: 390
    p47_UBX; p47-like ubiquitin domain
    smart00553
    Location:180272
    Blast Score: 408
    SEP; Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47
    pfam14555
    Location:648
    Blast Score: 161
    UBA_4; UBA-like domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000068.7 

    Range
    151494187..151511308
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499844.1XP_006499907.1  

    Related
    ENSMUSP00000028949, OTTMUSP00000016842, ENSMUST00000028949, OTTMUST00000037574
    Conserved Domains (3) summary
    cd01770
    Location:292370
    Blast Score: 391
    p47_UBX; p47-like ubiquitin domain
    smart00553
    Location:178270
    Blast Score: 409
    SEP; Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47
    pfam14555
    Location:648
    Blast Score: 161
    UBA_4; UBA-like domain

Alternate Mm_Celera

Genomic

  1. AC_000024.1 

    Range
    157311678..157328675
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Supplemental Content

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