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    flavivirus polyprotein gene flavivirus polyprotein [ West Nile virus ]

    Gene ID: 912267, updated on 27-Aug-2016
    Gene symbol
    flavivirus polyprotein gene
    Gene description
    flavivirus polyprotein
    Locus tag
    WNVgp1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    West Nile virus (strain: 956, gb-acronym: WNV)
    Lineage
    Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus; Japanese encephalitis virus group
    Location:
    clone: 33/G8; 34/F6
    Sequence:
    NC_001563.2 (97..10389)

    NC_001563.2Genomic Context describing neighboring genes

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description
    Names
    flavivirus polyprotein
    truncated flavivirus polyprotein NS1 prime
    capsid protein C
    anchored capsid protein C
    membrane glycoprotein precursor M
    membrane glycoprotein M
    envelope protein E
    nonstructural protein NS1
    nonstructural protein NS2A
    nonstructural protein NS2B
    nonstructural protein NS3
    nonstructural protein NS4A
    protein 2K
    nonstructural protein NS4B
    RNA-dependent RNA polymerase NS5
    protein pr
    nonstructural protein NS1 prime
    YP_009164950.1
    • NS1' protein; transframe fusion protein expressed via programmed ribosomal frameshifting; when frameshifting occurs, cleavage between NS1 and NS2A fails to occur

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001563.2 Reference assembly

      Range
      97..10389
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_041724.2 flavivirus polyprotein [West Nile virus]

      See identical proteins and their annotated locations for NP_041724.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P06935
      Conserved Domains (20) summary
      pfam01003
      Location:6105
      Flavi_capsid; Flavivirus capsid protein C
      pfam01003
      Location:6123
      Flavi_capsid; Flavivirus capsid protein C
      pfam01004
      Location:98167
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:781
      Flavi_propep; Flavivirus polyprotein propeptide
      pfam01004
      Location:675
      Flavi_M; Flavivirus envelope glycoprotein M
      cd12149
      Location:304396
      Flavi_E_C; Immunoglobulin-like domain III (C-terminal domain) of Flavivirus envelope glycoprotein E
      TIGR04240
      Location:401497
      flavi_E_stem; flavivirus envelope glycoprotein E, stem/anchor domain
      pfam00869
      Location:3295
      Flavi_glycoprot; Flavivirus glycoprotein, central and dimerization domains
      pfam00948
      Location:2352
      Flavi_NS1; Flavivirus non-structural Protein NS1
      pfam01005
      Location:12164
      Flavi_NS2A; Flavivirus non-structural protein NS2A
      pfam01002
      Location:4131
      Flavi_NS2B; Flavivirus non-structural protein NS2B
      smart00487
      Location:181326
      DEXDc; DEAD-like helicases superfamily
      pfam00949
      Location:19167
      Peptidase_S7; Peptidase S7, Flavivirus NS3 serine protease
      pfam07652
      Location:186331
      Flavi_DEAD; Flavivirus DEAD domain
      cl21455
      Location:357465
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
      pfam01350
      Location:5126
      Flavi_NS4A; Flavivirus non-structural protein NS4A
      pfam01349
      Location:1250
      Flavi_NS4B; Flavivirus non-structural protein NS4B
      pfam00972
      Location:254894
      Flavi_NS5; Flavivirus RNA-directed RNA polymerase
      pfam01728
      Location:55223
      FtsJ; FtsJ-like methyltransferase
      pfam01570
      Location:791
      Flavi_propep; Flavivirus polyprotein propeptide
    2. YP_009164950.1 truncated flavivirus polyprotein NS1 prime [West Nile virus]

      Status: PROVISIONAL

      Conserved Domains (7) summary
      cd12149
      Location:594686
      Flavi_E_C; Immunoglobulin-like domain III (C-terminal domain) of Flavivirus envelope glycoprotein E
      TIGR04240
      Location:691787
      flavi_E_stem; flavivirus envelope glycoprotein E, stem/anchor domain
      pfam01003
      Location:6123
      Flavi_capsid; Flavivirus capsid protein C
      pfam00869
      Location:293585
      Flavi_glycoprot; Flavivirus glycoprotein, central and dimerization domains
      pfam00948
      Location:7891139
      Flavi_NS1; Flavivirus non-structural Protein NS1
      pfam01004
      Location:221290
      Flavi_M; Flavivirus envelope glycoprotein M
      pfam01570
      Location:130204
      Flavi_propep; Flavivirus polyprotein propeptide
    3. YP_009164952.1 nonstructural protein NS1 prime

      Conserved Domains (1) summary
      pfam00948
      Location:2352
      Flavi_NS1; Flavivirus non-structural Protein NS1