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ECA3 calcium-transporting ATPase 3, ER-type [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837550, updated on 24-Jan-2015
Gene symbol
ECA3
Gene description
calcium-transporting ATPase 3, ER-type
Primary source
TAIR:AT1G10130
Locus tag
AT1G10130
Gene type
protein coding
RNA name
calcium-transporting ATPase 3, ER-type
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA ER-TYPE CA2+-ATPASE 3; ATECA3; ECA3; endoplasmic reticulum-type calcium-transporting ATPase 3; T27I1.16; T27I1_16
Summary
Encodes a golgi localized P2A-type Ca2+ ATPase involved in Mn nutrition and homeostasis.
See ECA3 in MapViewer
Location:
chromosome: 1
Exon count:
34
Sequence:
Chromosome: 1; NC_003070.9 (3310930..3322213)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene F-box family protein Neighboring gene transcription factor bHLH74 Neighboring gene hypothetical protein Neighboring gene Carbohydrate-binding protein

Homology

  • Homologs of the ECA3 gene: The ECA3 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, M.oryzae, N.crassa, rice, and frog.
NM_100887.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
calcium-transporting ATPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium-transporting ATPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
calmodulin binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
manganese-transporting ATPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
calcium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
intra-Golgi vesicle-mediated transport RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
manganese ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
manganese ion transport IGI
Inferred from Genetic Interaction
more info
PubMed 
membrane fusion RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
root development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
cell RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
endomembrane system IDA
Inferred from Direct Assay
more info
PubMed 
endosome IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
late endosome membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus ISM
Inferred from Sequence Model
more info
 
trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 
Names
calcium-transporting ATPase 3, ER-type
NP_563860.1
  • endoplasmic reticulum-type calcium-transporting ATPase 3 (ECA3); FUNCTIONS IN: manganese-transporting ATPase activity, calcium-transporting ATPase activity, calmodulin binding; INVOLVED IN: manganese ion transport, calcium ion transport, root development, manganese ion homeostasis; LOCATED IN: endomembrane system, Golgi apparatus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, calcium-transporting (InterPro:IPR005782), ATPase, P-type, H+ transporting proton pump (InterPro:IPR000695), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type phosphorylation site (InterPro:IPR018303), ATPase, P-type cation-transporter, C-terminal (InterPro:IPR006068); BEST Arabidopsis thaliana protein match is: endomembrane-type CA-ATPase 4 (TAIR:AT1G07670.1); Has 52019 Blast hits to 33942 proteins in 3233 species: Archae - 1100; Bacteria - 36533; Metazoa - 4334; Fungi - 2931; Plants - 2474; Viruses - 3; Other Eukaryotes - 4644 (source: NCBI BLink).

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 

    Range
    3310930..3322213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100887.2NP_563860.1  calcium-transporting ATPase 3, ER-type [Arabidopsis thaliana]

    See proteins identical to NP_563860.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SY55
    Conserved Domains (6) summary
    cd01427
    Location:592709
    HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
    pfam00122
    Location:92337
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:776973
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:472
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:415524
    Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit
    TIGR01116
    Location:53975
    ATPase-IIA1_Ca; sarco/endoplasmic reticulum calcium-translocating P-type ATPase