Display Settings:

Format

Send to:

Choose Destination

CHD3 chromodomain helicase DNA binding protein 3 [ Homo sapiens (human) ]

Gene ID: 1107, updated on 23-Sep-2014
Official Symbol
CHD3provided by HGNC
Official Full Name
chromodomain helicase DNA binding protein 3provided by HGNC
Primary source
HGNC:HGNC:1918
See related
Ensembl:ENSG00000170004; HPRD:09071; MIM:602120; Vega:OTTHUMG00000150427
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZFH; Mi-2a; Mi2-ALPHA
Summary
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
See CHD3 in Epigenomics, MapViewer
Location:
17p13.1
Exon count:
44
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 17 NC_000017.11 (7884780..7912757)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (7788096..7816075)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene transmembrane protein 88 Neighboring gene uncharacterized LOC102724217 Neighboring gene N(alpha)-acetyltransferase 38, NatC auxiliary subunit Neighboring gene cytochrome b5 domain containing 1 Neighboring gene small Cajal body-specific RNA 21 Neighboring gene uncharacterized LOC284023 Neighboring gene potassium voltage-gated channel, shaker-related subfamily, beta member 3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Protein interactions

Protein Gene Interaction Pubs
Tat tat Depletion of CHD3 results in derepression of latent HIV-1 LTR activity PubMed

Go to the HIV-1, Human Interaction Database

  • Chromatin modifying enzymes, organism-specific biosystem (from REACTOME)
    Chromatin modifying enzymes, organism-specific biosystemEukaryotic DNA is associated with histone proteins and organized into a complex nucleoprotein structure called chromatin. This structure decreases the accessibility of DNA but also helps to protect i...
  • Chromatin organization, organism-specific biosystem (from REACTOME)
    Chromatin organization, organism-specific biosystemChromatin organization refers to the composition and conformation of complexes between DNA, protein and RNA. It is determined by processes that result in the specification, formation or maintenance o...
  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • HDACs deacetylate histones, organism-specific biosystem (from REACTOME)
    HDACs deacetylate histones, organism-specific biosystemLysine deacetylases (KDACs), historically referred to as histone deacetylases (HDACs), are divided into the Rpd3/Hda1 metal-dependent 'classical HDAC family' (de Ruijter et al. 2003, Verdin et al. 2...
  • RNA Polymerase I Promoter Clearance, organism-specific biosystem (from REACTOME)
    RNA Polymerase I Promoter Clearance, organism-specific biosystemPromoter clearance is one of the rate-limiting steps in Polymerase I transcription. This step is composed of three phases, promoter opening, transcription initiation and promoter escape.
  • RNA Polymerase I Transcription, organism-specific biosystem (from REACTOME)
    RNA Polymerase I Transcription, organism-specific biosystemThe rRNA genes are transcribed by RNA polymerase I, one of three eukaryotic nuclear RNA polymerases. The polymerase is a multisubunit complex, composed of two large subunits (the most conserved porti...
  • RNA Polymerase I Transcription Initiation, organism-specific biosystem (from REACTOME)
    RNA Polymerase I Transcription Initiation, organism-specific biosystemDuring initiation the double-stranded DNA must be melted and transcription begins. SL1 forms and interacts with UBF-1 and the rDNA promoter. It is this platform that will recruit active RNA polymeras...
  • RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem (from REACTOME)
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystemTranscription by RNA Polymerase I, RNA Polymerase III and transcription from mitochondrial promoters.
  • Signaling events mediated by HDAC Class I, organism-specific biosystem (from Pathway Interaction Database)
    Signaling events mediated by HDAC Class I, organism-specific biosystem
    Signaling events mediated by HDAC Class I
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP-dependent DNA helicase activity TAS
Traceable Author Statement
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
helicase activity NAS
Non-traceable Author Statement
more info
PubMed 
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
zinc ion binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
ATP catabolic process IEA
Inferred from Electronic Annotation
more info
 
DNA duplex unwinding TAS
Traceable Author Statement
more info
PubMed 
centrosome organization IDA
Inferred from Direct Assay
more info
PubMed 
chromatin assembly or disassembly IEA
Inferred from Electronic Annotation
more info
 
chromatin modification IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription from RNA polymerase II promoter TAS
Traceable Author Statement
more info
PubMed 
regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
spindle organization IDA
Inferred from Direct Assay
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
NuRD complex IDA
Inferred from Direct Assay
more info
PubMed 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
intermediate filament cytoskeleton IDA
Inferred from Direct Assay
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
Preferred Names
chromodomain-helicase-DNA-binding protein 3
Names
chromodomain-helicase-DNA-binding protein 3
hZFH
CHD-3
zinc finger helicase
ATP-dependent helicase CHD3
mi-2 autoantigen 240 kDa protein
zinc-finger helicase (Snf2-like)
NP_001005271.2
NP_001005273.1
NP_005843.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005271.2NP_001005271.2  chromodomain-helicase-DNA-binding protein 3 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and CDS, compared to variant 1, resulting in a longer protein (isoform 3) that has a distinct N-terminus, compared to isoform 1. The transcript is supported by ESTs and an mRNA but the predicted protein has not yet been confirmed experimentally.
    Source sequence(s)
    AF064844, AK125928, BC110648, BX283837, CB851648, U91543
    Consensus CDS
    CCDS32553.2
    UniProtKB/TrEMBL
    B3KWV4
    UniProtKB/Swiss-Prot
    Q12873
    UniProtKB/TrEMBL
    Q2TAZ1
    Related
    ENSP00000369716, OTTHUMP00000197337, ENST00000380358, OTTHUMT00000318052
    Conserved Domains (10) summary
    COG1111
    Location:9381317
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161241
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam06461
    Location:14391576
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13711416
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17941966
    CHDCT2; CHDCT2 (NUC038) domain
  2. NM_001005273.2NP_001005273.1  chromodomain-helicase-DNA-binding protein 3 isoform 1

    See proteins identical to NP_001005273.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variant 1 encodes isoform 1.
    Source sequence(s)
    AK125928, BC110648, CB851648, U91543
    Consensus CDS
    CCDS32554.1
    UniProtKB/TrEMBL
    B3KWV4
    UniProtKB/Swiss-Prot
    Q12873
    UniProtKB/TrEMBL
    Q2TAZ1
    Related
    ENSP00000332628, OTTHUMP00000197335, ENST00000330494, OTTHUMT00000318050
    Conserved Domains (10) summary
    COG1111
    Location:8791258
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:628683
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:756914
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:10571182
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7391035
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:458502
    PHD; PHD-finger
    pfam06461
    Location:13801517
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13121357
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:147201
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17351907
    CHDCT2; CHDCT2 (NUC038) domain
  3. NM_005852.3NP_005843.2  chromodomain-helicase-DNA-binding protein 3 isoform 2

    See proteins identical to NP_005843.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' CDS, compared to variant 1. The resulting protein (isoform 2) is shorter, compared to isoform 1.
    Source sequence(s)
    AK125928, BC110648, CB851648, U91543
    Consensus CDS
    CCDS32555.1
    UniProtKB/TrEMBL
    B3KWV4
    UniProtKB/Swiss-Prot
    Q12873
    UniProtKB/TrEMBL
    Q2TAZ1
    Related
    ENSP00000350907, OTTHUMP00000197336, ENST00000358181, OTTHUMT00000318051
    Conserved Domains (11) summary
    PHA03418
    Location:15191654
    PHA03418; hypothetical E4 protein; Provisional
    COG1111
    Location:8791258
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:628683
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:756914
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:10571182
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7391035
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:458502
    PHD; PHD-finger
    pfam06461
    Location:13801517
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13121357
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:147201
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17011873
    CHDCT2; CHDCT2 (NUC038) domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000017.11 

    Range
    7884780..7912757
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005256431.2XP_005256488.1  

    Conserved Domains (6) summary
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161184
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
  2. XM_005256427.2XP_005256484.1  

    Conserved Domains (10) summary
    COG1111
    Location:9381317
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161241
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam06461
    Location:14391576
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13711416
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17951923
    CHDCT2; CHDCT2 (NUC038) domain
  3. XM_005256429.2XP_005256486.1  

    Conserved Domains (10) summary
    COG1111
    Location:9381317
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161241
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam06461
    Location:14391576
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13711416
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17951967
    CHDCT2; CHDCT2 (NUC038) domain
  4. XM_006721426.1XP_006721489.1  

    Conserved Domains (11) summary
    PHA03418
    Location:15781727
    PHA03418; hypothetical E4 protein; Provisional
    COG1111
    Location:9381317
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161241
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam06461
    Location:14391576
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13711416
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17951925
    CHDCT2; CHDCT2 (NUC038) domain
  5. XM_006721423.1XP_006721486.1  

    Conserved Domains (10) summary
    COG1111
    Location:9381317
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161241
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam06461
    Location:14391576
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13711416
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17941922
    CHDCT2; CHDCT2 (NUC038) domain
  6. XM_005256428.2XP_005256485.1  

    Conserved Domains (11) summary
    PHA03418
    Location:15781713
    PHA03418; hypothetical E4 protein; Provisional
    COG1111
    Location:9381317
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161241
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam06461
    Location:14391576
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13711416
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17601888
    CHDCT2; CHDCT2 (NUC038) domain
  7. XM_006721428.1XP_006721491.1  

    Conserved Domains (11) summary
    PHA03418
    Location:15781713
    PHA03418; hypothetical E4 protein; Provisional
    COG1111
    Location:9381317
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161241
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam06461
    Location:14391576
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13711416
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17601932
    CHDCT2; CHDCT2 (NUC038) domain
  8. XM_006721424.1XP_006721487.1  

    Conserved Domains (10) summary
    COG1111
    Location:9341313
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:683738
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:811969
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11121237
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7941090
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:513557
    PHD; PHD-finger
    pfam06461
    Location:14351572
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13671412
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17911919
    CHDCT2; CHDCT2 (NUC038) domain
  9. XM_006721430.1XP_006721493.1  

    Conserved Domains (10) summary
    COG1111
    Location:9341313
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:683738
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:811969
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11121237
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7941090
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:513557
    PHD; PHD-finger
    pfam06461
    Location:14351572
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13671412
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17911963
    CHDCT2; CHDCT2 (NUC038) domain
  10. XM_006721429.1XP_006721492.1  

    Conserved Domains (10) summary
    COG1111
    Location:9381317
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:687742
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:815973
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:11161241
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7981094
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:517561
    PHD; PHD-finger
    pfam06461
    Location:14391576
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13711416
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:206260
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17951924
    CHDCT2; CHDCT2 (NUC038) domain
  11. XM_006721427.1XP_006721490.1  

    Conserved Domains (10) summary
    COG1111
    Location:8591238
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:608663
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:736894
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:10371162
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7191015
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:438482
    PHD; PHD-finger
    pfam06461
    Location:13601497
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:12921337
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:127181
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17161844
    CHDCT2; CHDCT2 (NUC038) domain
  12. XM_006721425.1XP_006721488.1  

    Conserved Domains (10) summary
    COG1111
    Location:8791258
    MPH1; ERCC4-like helicases [DNA replication, recombination, and repair]
    cd00024
    Location:628683
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:756914
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:10571182
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:7391035
    SNF2_N; SNF2 family N-terminal domain
    pfam00628
    Location:458502
    PHD; PHD-finger
    pfam06461
    Location:13801517
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13121357
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:147201
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17361864
    CHDCT2; CHDCT2 (NUC038) domain

Alternate HuRef

Genomic

  1. AC_000149.1 

    Range
    7683207..7710664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018928.2 

    Range
    7797025..7824854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)