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    Sctr secretin receptor [ Mus musculus (house mouse) ]

    Gene ID: 319229, updated on 26-Jun-2016
    Official Symbol
    Sctrprovided by MGI
    Official Full Name
    secretin receptorprovided by MGI
    Primary source
    MGI:MGI:2441720
    See related
    Ensembl:ENSMUSG00000026387 Vega:OTTMUSG00000049072
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6530402O03Rik
    Orthologs
    Location:
    1; 1 E2.3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (120006899..120063539)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (121903557..121960111)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 221 Neighboring gene ribosomal protein L9 pseudogene Neighboring gene predicted gene, 33817 Neighboring gene predicted gene, 33764 Neighboring gene predicted gene, 41936 Neighboring gene transmembrane protein 37 Neighboring gene predicted gene, 41937

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC102218

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptide binding ISO
    Inferred from Sequence Orthology
    more info
     
    secretin receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cAMP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    secretin receptor
    Names
    SCT-R

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012322.2NP_001012322.2  secretin receptor isoform 1 precursor

      See identical proteins and their annotated locations for NP_001012322.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK032652, BC089355
      Consensus CDS
      CCDS48341.1
      UniProtKB/Swiss-Prot
      Q5FWI2
      UniProtKB/TrEMBL
      H7BX37
      Related
      ENSMUSP00000072660, OTTMUSP00000067979, ENSMUST00000072886, OTTMUST00000125325
      Conserved Domains (2) summary
      pfam00002
      Location:153398
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:79140
      HRM; Hormone receptor domain
    2. NM_001311077.1NP_001298006.1  secretin receptor isoform 2 precursor

      See identical proteins and their annotated locations for NP_001298006.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon and uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AK032652, BC089355
      Consensus CDS
      CCDS78668.1
      UniProtKB/Swiss-Prot
      Q5FWI2
      Related
      ENSMUSP00000139932, OTTMUSP00000067980, ENSMUST00000189037, OTTMUST00000125326
      Conserved Domains (2) summary
      pfam00002
      Location:138383
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:63125
      HRM; Hormone receptor domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      120006899..120063539
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529685.3XP_006529748.1  

      Conserved Domains (2) summary
      pfam00002
      Location:153398
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:79140
      HRM; Hormone receptor domain
    2. XM_006529684.3XP_006529747.1  

      Conserved Domains (2) summary
      pfam00002
      Location:153398
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:79140
      HRM; Hormone receptor domain
    3. XM_006529686.3XP_006529749.1  

      Conserved Domains (2) summary
      pfam00002
      Location:138383
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:63125
      HRM; Hormone receptor domain
    4. XM_006529683.3XP_006529746.1  

      See identical proteins and their annotated locations for XP_006529746.1

      UniProtKB/TrEMBL
      H7BX37
      Conserved Domains (2) summary
      pfam00002
      Location:153398
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:79140
      HRM; Hormone receptor domain
    5. XM_011248029.1XP_011246331.1  

      See identical proteins and their annotated locations for XP_011246331.1

      Conserved Domains (2) summary
      pfam00002
      Location:67312
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:254
      HRM; Hormone receptor domain
    6. XM_006529688.3XP_006529751.1  

      See identical proteins and their annotated locations for XP_006529751.1

      Conserved Domains (2) summary
      pfam00002
      Location:67312
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:254
      HRM; Hormone receptor domain
    7. XM_011248030.2XP_011246332.1  

      See identical proteins and their annotated locations for XP_011246332.1

      Conserved Domains (2) summary
      pfam00002
      Location:67312
      7tm_2; 7 transmembrane receptor (Secretin family)
      pfam02793
      Location:254
      HRM; Hormone receptor domain
    8. XM_011248031.2XP_011246333.1  

      Conserved Domains (2) summary
      pfam00002
      Location:62307
      7tm_2; 7 transmembrane receptor (Secretin family)
      cl02422
      Location:2149
      HRM; Hormone receptor domain
    9. XM_006529689.3XP_006529752.1  

      Conserved Domains (1) summary
      pfam00002
      Location:46262
      7tm_2; 7 transmembrane receptor (Secretin family)
    10. XM_006529690.3XP_006529753.1  

      Conserved Domains (1) summary
      cl21587
      Location:1166
      7tm_2; 7 transmembrane receptor (Secretin family)