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SUGP1 SURP and G patch domain containing 1 [ Homo sapiens (human) ]

Gene ID: 57794, updated on 13-Jan-2015
Official Symbol
SUGP1provided by HGNC
Official Full Name
SURP and G patch domain containing 1provided by HGNC
Primary source
HGNC:HGNC:18643
See related
Ensembl:ENSG00000105705; HPRD:10468; MIM:607992; Vega:OTTHUMG00000182223
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RBP; SF4; F23858
Summary
SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003]
Orthologs
See SUGP1 in MapViewer
Location:
19p13.11
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 19 NC_000019.10 (19276511..19320512, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (19387320..19431321, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene hyaluronan and proteoglycan link protein 4 Neighboring gene transmembrane 6 superfamily member 2 Neighboring gene MAU2 sister chromatid cohesion factor Neighboring gene GATA zinc finger domain containing 2A Neighboring gene microRNA 640

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Biological, clinical and population relevance of 95 loci for blood lipids.
NHGRI GWA Catalog
Common variants at 30 loci contribute to polygenic dyslipidemia.
NHGRI GWA Catalog
Discovery and refinement of loci associated with lipid levels.
NHGRI GWA Catalog
Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
NHGRI GWA Catalog
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
NHGRI GWA Catalog
  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem (from REACTOME)
    Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystemCo-transcriptional pre-mRNA splicing is not obligatory. Pre-mRNA splicing begins co-transcriptionally and often continues post-transcriptionally. Human genes contain an average of nine introns per ge...
  • mRNA Splicing, organism-specific biosystem (from REACTOME)
    mRNA Splicing, organism-specific biosystemThe process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, is called mRNA splicing...
  • mRNA Splicing - Major Pathway, organism-specific biosystem (from REACTOME)
    mRNA Splicing - Major Pathway, organism-specific biosystemThe splicing of pre-mRNA occurs within a large, very dynamic complex, designated the 'spliceosome'. The 50-60S spliceosomes are estimated to be 40-60 nm in diameter, and have molecular weights in the...
  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemThis process describes the conversion of precursor messenger RNA into mature messenger RNA (mRNA). The pre-mRNA molecule undergoes three main modifications. These modifications are 5' capping, 3' po...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp434E2216

Gene Ontology Provided by GOA

Function Evidence Code Pubs
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
RNA splicing TAS
Traceable Author Statement
more info
 
gene expression TAS
Traceable Author Statement
more info
 
mRNA splicing, via spliceosome TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
nucleoplasm TAS
Traceable Author Statement
more info
 
spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
SURP and G-patch domain-containing protein 1
Names
SURP and G-patch domain-containing protein 1
splicing factor 4
RNA-binding protein RBP

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172231.3NP_757386.2  SURP and G-patch domain-containing protein 1

    See proteins identical to NP_757386.2

    Status: VALIDATED

    Source sequence(s)
    AY072917, DC363162
    Consensus CDS
    CCDS12399.1
    UniProtKB/Swiss-Prot
    Q8IWZ8
    Related
    ENSP00000247001, OTTHUMP00000268677, ENST00000247001, OTTHUMT00000460128
    Conserved Domains (2) summary
    smart00443
    Location:560606
    G_patch; glycine rich nucleic binding domain
    pfam01805
    Location:188242
    Surp; Surp module

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000019.10 

    Range
    19276511..19320512
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005260002.1XP_005260059.1  

    See proteins identical to XP_005260059.1

    UniProtKB/TrEMBL
    A0A024R7N3
    Conserved Domains (2) summary
    smart00443
    Location:350396
    G_patch; glycine rich nucleic binding domain
    pfam01805
    Location:54107
    Surp; Surp module

Alternate CHM1_1.1

Genomic

  1. NC_018930.2 

    Range
    19388088..19432088
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000151.1 

    Range
    18951058..18994630
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_021164.2: Suppressed sequence

    Description
    NM_021164.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
  2. NM_182812.1: Suppressed sequence

    Description
    NM_182812.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.